Biomedical subjects

Dennis Smiler

Publications and source records attributed to Dennis Smiler.

2 recordsLinked to original sources

PubMed2006

The bone-grafting decision tree: a systematic methodology for achieving new bone.

Successful bone grafting requires that the clinician select the optimal bone grafting material and surgical technique from among a number of alternatives. This article reviews the biology of bone growth and repair, and presents a decision-making protocol in which the clinician first evaluates the bone quality at the surgical site to determine which graft material should be used. Bone quantity is then evaluated to determine the optimal surgical technique. Choices among graft stabilization techniques are also reviewed, and cases are presented to illustrate the use of this decision tree.

Bone Regeneration↗

PubMed2006

Bone marrow aspiration: technique, grafts, and reports.

This article describes a technique for obtaining adult stem cells from bone marrow aspirate. Case reports show how this procedure might replace the gold standard for bone grafts with the platinum standard of obtaining stem cells. The bone marrow aspirate and transplantation of adult stem cells within the resorbable) matrix and under the influence of soluble regulators have the potential for introducing the platinum standard for bone grafts. There are several advantages to using bone marrow aspirate. The technique is simple, a second surgical site is not needed, there is minimal postoperative morbidity, and adult stem cells populate the graft site with osteoblasts.

Adult↗