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Dilek Senen

Publications and source records attributed to Dilek Senen.

10 recordsLinked to original sources
PubMed2002

Flipper hand.

Explore the source record for details and available documents.

Adult↗
PubMed2002

Effects of different vascular patterns and the delay phenomenon on rat ventral island flap viability.

The objective of the current study was to investigate flap viability and to determine optimal delay time by designing various blood flow patterns in the superficial inferior epigastric (SIE) artery (A) and vein (V) flap model. Flaps measuring 7 x 7 cm were created in 42 Sprague-Dawley rats, which were divided into six groups. In group I rats (AV-AV), the flap was elevated based on the bilateral SIE vessels. In group II rats (AV-A), the flap was elevated based on the right SIE vessels and the left artery. In group III rats (V-AV), the flap was elevated based on the left-side vein whereas the SIE artery and vein were the pedicle on the right side. In group IV rats (V-A), the flap was elevated as a venous flap on the left side and was SIE artery based on the right side. In group V rats (AV-) the flap was elevated based on the right SIE artery and vein. In group VI rats (delay), the SIA artery and vein on the left side were ligated without elevation during the first session. The flap was elevated on the right SIE artery and vein 7 days after the delay procedure. Percentages of viable flap surface area were measured in millimeters with acetate paper on day 5 after surgery. The highest viability was seen in group I rats (96.14%), and the delay group had the second highest viable area (88.56%). The area that remained viable in group II was larger than that of group III (87.41% vs. 72.84%; p < 0.05). The least viable areas were observed in group IV. The percentage of viable flap area was significantly higher in the delay group when compared with group V rats (88.56 +/- 1.06% vs. 60.01 2.58%; p < 0.05). In conclusion, if the contralateral pedicle is ligated 7 days before SIE vessel-based island flap elevation, the flap can be used safely in a manner that crosses the median. Artery inflow of the flap is more important than venous outflow for improvement of flap viability on the contralateral side.

Animals↗
PubMedDate not supplied

Contribution of vitamin C administration for increasing lipolysis.

This experiment was designed to investigate whether addition of vitamin C to the solution used in tumescent technique of liposuction might increase lipolysis and whether increased fibrosis might improve skin retraction where liposuction did not work properly and the skin had poor retraction ability. Eighteen Sprague-Dawley rats were used in two groups. Both inguinal fat pads of rats with their vascular structures were elevated and the right inguinal fat pad was injected with 1 cc tumescent solution as a control and the left fat pad with a 1 cc vitamin C-tumescent solution. Histopathological examination showed that all fat pads injected with tumescent solution had normal adipocytes. Those injected with vitamin C-tumescent were shown to have extreme fibrosis and occasional adipocytes.

Adipose Tissue↗
PubMedDate not supplied

Cryopreservation of hair follicles at 20 degrees C: can it work in staged hair transplantation.

Androgenic alopecia is a serious problem for a large proportion of the population, especially males, and causes them to seek medical help. Many methods have been described for treatment of androgenic alopesia. Among them are punch grafts, strip grafts, scalp grafts, scalp reductions, tissue expanders, and flap combinations, and hair transplantations with minigrafts and micrografts. The latter has become popular in the last two to three decades and has been investigated extensively. Improvements in hair replacement with minigrafts and micrografts may allow an ideal result with a nearly normal appearance. However, hair replacement with these grafts has important disadvantages. It requires a long operational time and only a limited number of grafts can be placed in one session. In this study, we investigated morphological structures of micrografts stored at 4 degrees C and those stored at -20 degrees C. We found that morphological structures of the grafts stored at 4 degrees C started to be impaired in the fifth day, but that the morphological structures of the grafts stored at -20 degrees C remained unaltered for 15 days. If this method is put into practice, the use of minigrafts and micrografts available will not only obviate the second graft harvesting, but also allow reconstruction of a large area in a short period of time.

Adult↗