Ding Lin | PubMed Health

PubMed2006

[Relationship between right ventricular mechanical delay and right ventricular systolic function in patients with pulmonary hypertension].

OBJECTIVE: To investigate the relationship between right ventricular (RV) mechanical delay and RV dysfunction in patients with pulmonary hypertension (PH). METHODS: A total of 51 patients with PH were divided into mild, moderate and high PH groups and 30 healthy volunteers served as control group. RV mechanical delay (defined as the difference in time to peak systolic annular velocity between the RV free wall and the ventricular septum) and RV fractional area change were obtained on apical four chamber view with Quantitive Tissue Velocity Imaging (QTVI). RESULTS: RV mechanical delay increases in proportion to pulmonary pressure. RV fractional area change was similar between control and mild PH patients while significantly reduced in moderate and high PH patients compared to controls. RV mechanical delay significantly correlated to RV fractional area change in all PH groups (r = -0.79; r = -0.66; r = -0.80, all P < 0.05). CONCLUSION: RV mechanical delay measured by QTVI can be used to evaluate RV dysfunction in patients with pulmonary hypertension.

Adolescent↗

PubMed2005

[Intermediate-term and long-term clinical evaluation of the Ahmed glaucoma valve implantation].

OBJECTIVE: To evaluate the Intermediate-term and long-term clinical results of Ahmed glaucoma valve (AGV) implantation in refractory glaucoma. METHODS: A retrospective study was conducted to document 221 eyes from 206 patients with refractory glaucoma who undergone AGV implantation or combined AGV implantation with other intraocular surgery. The subject had a minimum 6 months of follow-up after surgery. According to the successful definition of AGV implantation, life table's analysis was used to assess the cumulative probabilities of success in different follow-up time. Cox regression analysis was performed to estimate the relationships between survival outcomes and multiple predictors. RESULTS: The follow-up ranged from 6.03 to 86.30 months (mean 36.86 months). The cumulative probabilities of success at 0.5, 1, 2, 3, and 4 years were (88.5 +/- 2.2)%, (85.0 +/- 2.5)%, (76.4 +/- 3.1)%, (66.2 +/- 3.7)%, (55.5 +/- 4.7)% and of total success at 0.5, 1, 2, 3, and 4 years were (91.2 +/- 1.9)%, (88.6 +/- 2.2)%, (88.6 +/- 2.2)%, (86.8 +/- 2.5)%, (86.8 +/- 2.5)%, respectively. Intraocular pressure was reduced from a preoperative mean of (44.59 +/- 13.04) mm Hg (1 mm Hg = 0.133 kPa) to a postoperative mean of (16.52 +/- 4.61) mm Hg (P < 0.01). The early major complications included transient hypotony (19.5%), shallow anterior chamber (14.5%), tube blockage (11.3%), hemorrhage (7.2%). The late major complications were encapsulated bleb (10.9%), exposure of tube (5.0%), tube malposition (4.5%), corneal decompensation (2.3%), extrusion of implant (1.4%). CONCLUSIONS: AGV or combined AGV with other intraocular surgery is effective and relatively safe method for treating refractory glaucoma. The rates of success can be increased by means of effective management of the complications.

Adolescent↗