Biomedical subjects

Domagoj Glavina

Publications and source records attributed to Domagoj Glavina.

5 recordsLinked to original sources

PubMed2006

[Clinical evaluation of three different materials for fissure sealing after 12 months].

AIM: Fissure sealing is a preventive and therapeutic procedure by which the occlusal surface of the fissure system of the teeth is closed with sealing materials for prevention and therapy of initial caries. The fissures of the teeth treated with sealing materials become physiologically clean spots, with no possibility for the developement of caries lesion. The aim of the study was to clinically compare three different fissure sealing materials after one year of use. METHODS: The study included 73 subjects, 29 (39.7%) male, and 44 (60.3%) female, aged 7-21 years. Sealing was carried out on 150 healthy permenant molars with three different sealing materials divided into three groups: Teethmate F1 (Kuraray) in 48 teeth, Helioseal Clear Chroma (Vivadent) in 52 teeth, and Tetric Flow (Vivadent) in 50 teeth. In each subject, at least two different sealing materials were used. On analysis of the degree of retention and occurrence of secondary caries lesion, modified criteria described by Kilpatrick et al. (1996) were used: 0=no loss, 1=loss of 1/3 of the seal, 2=loss of 2/3 of the seal, 3=complete loss of the seal (more than 2/3 of the material). The criteria for evaluation of the occurrence of secondary caries were: 0=no caries, 1=caries. RESULTS: After 12 months, complete retention of the Teethmate F1 material was 77.1%, of Helioseal Clear Chroma 76.9%, and of Tetric Flow 84%. There is no statistically significant difference in retention among the sealing materials after 12 months. Tetric Flow showed a better appearance of retention, although not statistically significant (p=0.287). Out of 150 sealed teeth, at 12 months caries was found in only 3 teeth: 2 in the group sealed with Teethmate F1 and one in the group sealed with Helioseal Clear Chroma. In the group sealed with Tetric Flow, no caries was recorded at 12 months. CONCLUSION: Comparison of the degree of retention showed flowable composite as a sealing material to yield better results than the classic sealing materials, although the difference was not statistically demonstrated. The low incidence of caries in the fissure system between sealed teeth indicated a good preventive action of the sealing materials. Because of the great supply of flowable composites on the market, differing in the content and consistency, and a great number of various enamel-dentin adhesive systems, there is a need of additional long-term research to determine their clinical justifiability.

Adolescent↗

PubMed2005

Labial talon cusp on maxillary central incisors: a rare developmental dental anomaly.

Labial talon cusp, or dens evaginatus is a very rare dental anomaly of unclear etiology and significance. It can occur as an isolated finding or be associated with other dental anomalies or some syndromes. The present report describes two Caucasian males with labial talon cusp on maxillary permanent left central incisors. In both cases accessory cusp caused plaque accumulation and marginal gingivitis. One case displayed affected tooth to be in cross bite position causing occlusal trauma. No other dental anomalies in either case, neither association with some syndromes were noted. This rare anomaly requires careful dental and physical examination of the affected patient since its finding can be of clinical and genetic significance.

Child↗

PubMed2004

Palatal and dental arch morphology in Down syndrome.

The analysis of palatal vault morphology and maxillary dental arch shape was carried out in the sample of 42 Down syndrome (DS) patients with trisomy 21. The data were compared to those of healthy controls from the same population matched for age and sex. Palatal morphology and upper dental arch shape were studied on hard plaster casts of the patients and controls. No sexual dimorphism in palatal and dental arch shape was observed in DS and controls. Normal palatal shape was more frequent in controls than in DS subjects (52.38% vs. 28.57%; p < 0.05). DS patients displayed significantly higher frequency of shelf-like or "stair palate" (38.1%) than controls (11.9%) (p < 0.02). The younger age group (3-14 year) showed much higher frequency of "stair palate" than controls (26.19% vs. 2.38%; c2 = 9.72; p = 0.003). The older group of DS patients did not show increased frequency of such shape of the palatal vault. There was no significant difference in dental arch shape between DS patients and controls. High frequency of shelf-like palate in DS subjects is decreasing by age. The obtained results indicate that palatal vault morphology is subjected to the age related changes. These changes can be attributed to the growth of caraniofacial structures and increased tonus of tongue and other orofacial muscles.

Adolescent↗

PubMed2003

Craniofacial anthropometric pattern profile in hypohidrotic ectodermal dysplasia--application in detection of gene carriers.

Hypohidrotic ectodermal dysplasia (HED) is characterized by clinical manifestations of severe hypodontia or anodontia, hypotrichosis, hypohidrosis, and specific facial appearance. Affected males show complete expression of clinical features of this condition. Their mothers, who are gene carriers, express only some signs, which are usually very mild. Currently available clinical methods are not sufficient for routine identification of the HED heterozygous gene carriers. The purpose of this study was to identify and describe the facial characteristics of HED patients and their mothers and to evaluate the usefulness of craniofacial pattern profile analysis (CFPP) in the diagnosis of this syndrome and the detection of gene carriers. In this study six affected males and their mothers were evaluated. Z-scores for each variable were calculated and compared with age- and sex-matched controls. Anthropometric analysis showed a specific dysmorphic pattern in CST patients that includes decreased skull base width (t-t: -1.67 Z); decreased forehead width (ft-ft: -1.8 Z), decreased midface depth (sn-t: -2.02 Z), markedly decreased total facial height (n-gn: -3.4 Z), and markedly decreased maxillary arc (t-sn-t: -2.5 Z). Gene carriers showed a similar tendency in their pattern profiles. They showed the same tendency towards lower Z-values for forehead width, facial height, and mouth width. The values for these measurements were between those of the affected and healthy controls. The most pronounced findings were increased head width (eu-eu: +2.83 Z), increased lower face width (go-go: +2.06 Z), and reduction of total facial height (n-gn: -0.95 Z). They also displayed increased nose width (al-al: +2.41 Z) and increased biocular distance (ex-ex: +2.01 Z). When used in conjunction with other methods the anthropometrics pattern profile analysis can considerably enhance detection of gene carriers for HED and increase objective assessment of the craniofacial region in HED patients.

Anodontia↗

PubMed2003

Dental and minor physical anomalies in children with developmental disorders--a discriminant analysis.

A discriminant analysis was performed in a sample of 303 children with developmental disorders (DD) and 303 healthy controls (C) in order to test whether some oro-dental and physical minor anomalies could discriminate these groups of children. DD sample comprised 176 mentally retarded (MR) children. 70 children with impaired hearing (IH) and 57 children with impaired vision (IV). The control group included 303 healthy subjects, matched for sex and age. The analysis comprised seven common oral and dental anomalies: median diastema, hypodontia, impacted teeth, microdontia, dens invaginatus, upper lip frenulum and frenulum of the tongue. Minor physical anomalies were assessed by the method proposed by Waldrop et al., as the average number of minor anomalies per individual (W1) and as the weighted score of minor anomalies (W2). Three discriminant functions were obtained by analysis of nine initial variables. Distinct discrimination and considerable distances were found between the centroids of the controls and all groups of DD children. The first two discriminant functions were significant for discrimination between the groups and they explained 98.6% of the total variance. The first function contained 90.2% of information and was defined by the number and weighted scores of minor anomalies. The second variable explained 8.4% of the total variability and was defined by three dental anomalies. The results obtained by the discriminant analysis show that application of dental and minor physical anomalies enables discrimination between the group of healthy children and the groups of children with different developmental disorders.

Adolescent↗