Biomedical subjects

Dominic A Simon

Publications and source records attributed to Dominic A Simon.

5 recordsLinked to original sources

PubMed2005

Relative processing demands influence cerebral laterality for verbal-motor integration in persons with Down syndrome.

The study of cerebral specialization in the Down syndrome (DS) population has revealed an anomalous pattern of organization. In particular, dichotic-listening studies have suggested a left-ear/right hemisphere dominance for speech perception, whereas motor control research has revealed a left hemisphere dominance for executive-motor control. In the present investigation, we employed a recent adaptation of the dichotic listening procedure to examine interhemispheric integration during the performance of a lateralized verbal-motor task. Specifically, using the selective dichotic-listening procedure, participants were required to complete a rapid left or right hand pointing movement to one of two pictorial icons corresponding to the word presented to their precued ear. We observed that persons with DS (N = 17) and age-matched controls (N = 35) exhibited a right-ear advantage (REA) for our dichotic-aiming task. While these results appear to contradict previous dichotic listening studies, we propose that the manifestation of a lateral ear advantage in the DS population may have more to do with the response requirements of the task than with the characteristics or complexity of the stimulus material.

Acoustic Stimulation↗

PubMed2003

Cerebral specialization and verbal-motor integration in adults with and without Down syndrome.

Persons with Down syndrome (DS) tend to exhibit an atypical left ear-right hemisphere advantage (LEA) for the perception of speech sounds. In the present study, a recent adaptation of the dichotic listening procedure was employed to examine interhemispheric integration during the performance of a lateralized verbal-motor task. Although adults with DS (n = 13) demonstrated a right ear-left hemisphere advantage in the dichotic-motor task similar to their peers with (n = 14) and without undifferentiated developmental disabilities (n = 14), they showed an LEA in a free recall dichotic listening task. Based on a comparison of the laterality indices obtained from both dichotic listening procedures, it appears that the manifestation of lateral ear advantages in persons DS may dependent on the response requirements of the task.

Adult↗

PubMed2003

Dichotic ear advantages in adults with Down's syndrome predict speech production errors.

Intellectually challenged adults, with and without Down's syndrome (DS), pointed to drawings of animals following the dichotic presentation of animal names. Although there were no reliable ear differences between the 2 groups, there was tremendous between-persons variability within the group of participants with DS. Moreover, left-ear advantages in persons with DS were associated with more speech production errors when participants either read or repeated a string of 1 syllable words. This was not true for control participants. The relationship between ear advantage and speech errors in persons with DS could reflect their unique pattern of cerebral specialization and brain development.

Adult↗

PubMed2002

Models of performance in learning multisegment movement tasks: consequences for acquisition, retention, and judgments of learning.

Participants learned different keystroke patterns, each requiring that a key sequence be struck in a prescribed time. Trials of a given pattern were either blocked or interleaved randomly with trials on the other patterns and before each trial modeled timing information was presented that either matched or mismatched the movement to be executed next. In acquisition, blocked practice and matching models supported better performance than did random practice and mismatching models. In retention, however, random practice and mismatching models were associated with superior learning. Judgments of learning made during practice were more in line with acquisition than with retention performance, providing further evidence that a learner's current ease of access to a motor skill is a poor indicator of learning benefit.

Adolescent↗

PubMed2002

Speech production errors in adults with and without Down syndrome following verbal, written, and pictorial cues.

Adults with Down syndrome and adults with developmental delays not related to Down syndrome were asked to read, repeat, and formulate speech from a picture following the presentation of 2- and 4-word and picture sequences. The speech sequences were produced either immediately after stimulus presentation or following a 5-sec response delay. Overall, participants with Down syndrome produced more memory errors than persons without Down syndrome. Participants with Down syndrome also committed more speech production errors than the other participants, but only when they were required to repeat what they had heard, or to formulate speech from pictures. The speech production performance of the two groups was equivalent in the read condition. These results are discussed with reference to Elliott, Weeks, and Elliott's (1987) model of cerebral specialization, and to verbal short-term memory in persons with Down syndrome.

Adult↗