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E A Dubtsova

Publications and source records attributed to E A Dubtsova.

6 recordsLinked to original sources
PubMed2005

[Anti-Helicobacter pylori antibodies in cases of stomach polyps].

UNLABELLED: The goal of the study was to study the content of anti-Helicobacter pylori antibodies (at-HP), their diagnostic and prognostic significance for stomach polyps. MATERIALS AND METHODS: The content of anti-Helicobacter antibodies (IgG-HP; IgA-HP; IgM + IgG + IgA-CagA-HP) was determined in the blood serum by way of immune-enzyme analysis of 46 patients with stomach polyps. Such test systems as EcoLab (Elektrostal) and Vector-Best (Novosibirsk) were used. RESULTS: Stomach polyps are accompanied by a regular increase of at-HP--serologic markers of helicobacteriosis content in the blood serum. The most significant increase in terms of percentage and absolute values is the IgG-HP concentration increase (88%, average titre 1: 1060, in the control group--1: 110) and summary (IgM + IgG + IgA) antibodies to CagA-HP (86%, average titre 1 : 180, in the control group 1 : 10), while the IgA-HP level is increased in 46%, average titre 1 : 660, in the control group 1 : 120). The IgG-HP content increase reflects the inflammatory process intensity, IgA-HP--atrophic process intensity, (IgM + IgG + IgA)-CagA-HP--1 intensity of proliferative processes of stomach polyps. CONCLUSION: The at-HP content increase is a diagnostic criterion for helicobacteriosis and reflects the intensity of infectious, inflammatory, atrophic and proliferative processes in cases of stomach polyps. A multiple long-lasting increase of the at-HP concentration may be one of the indications for administering an antihelicobacter stomach polyp therapy including administration before polypectomy.

Aged↗
PubMed2002

[Interleukins in stomach and duodenal ulcers].

The results of research have shown, that the ulcer disease is accompanied by the increase of peripheral blood interleukins. The maximal increase of interleukins quality and especially TNFa and interleukine-4 was revealed in the patients with peptic ulcer, that was diagnosed at the first time. Interleukins increase was less expressed in the patients with freguent ulcer relapses. In patients with UDS the level of interleukins at first revealed ulcer was a little bit higher, than at frequently relapsing ulcer, however contents of all investigated interleukins in UDS is rather lower than in ulcer disease of duodenum. The definition of cytokines profile in the patients with stomach and duodenal peptic ulcer has prognostic importance because it allows to receive the additional information about disease activity, its prognosis and efficiency of anti-ulcer's therapy.

Adolescent↗
PubMed2002

[Various immunological aspects of ulcer formation (a literature review)].

The duodenal ulcerative disease is accompanied by increase of blood serum interleukins, that is manifested not by only local, but also by common response of organism to damage. It is evidence of activation of T- and B-lymphocytes, endothelial and epithelial cells, of stimulation of apoptosis processes, of cellular differentiation and proliferation playing the important role in regeneration of duodenal mucous membrane. Therefore the definition of interleukin profile for ulcerative disease can have a prognostic value, as it allows to receive additional information regarding to activity of disease, its prognosis and respectively to efficiency of treatment.

Humans↗