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Biomedical subjects

E A Elebute

Publications and source records attributed to E A Elebute.

At least 19 recordsLinked to original sources
PubMed1983

The grading of sepsis.

A simple system for grading the severity of sepsis has been developed by scoring the attributes of sepsis under four headings: local effects of infection, pyrexia, secondary effects of sepsis and laboratory data. The information needed should be readily available at district general hospital level. The system produces a number which indicates the severity of sepsis and which varies with the patient's condition. This system could be useful in comparing patients with sepsis and studies on such patients in different centres.

Adult↗
PubMed1978

Constitutional factors and the local and general responses to injury.

The different constitutional factors which may affect the response to injury and the problems which must be considered in evaluating any injury model are discussed. Species, age, sex, nutrition and the presence of disease are discussed in relation to an injury model based on hind limb ischaemia, with reference to the extensive literature.

Aging↗
PubMed1978

Effect of streptozotocin-diabetes on the local and general responses to injury in the rat.

1. The effects of streptozotocin-diabetes on the local and general responses to a 4 h period of bilateral hind-limb ischaemia in the rat have been investigated. The rats were injured 48 h after the intravenous injection of the streptozotocin. 2. Less fluid was lost from the circulation into the injured limbs after injury in the diabetic rats and this was directly related to the severity of the diabetes, but could not be explained by dehydration. However, when the diabetic and nondiabetic injured rats were considered together there was significant negative correlation between either plasma osmolality or plasma glucose concentration and water content in the injured hind limb. 3. The relationship between plasma glucose concentration and plasma osmolality was changed by injury such that, particularly in the injured diabetic rats, plasma osmolality at a given glucose concentration was higher than that predicted from the relationship betweeen these variables in the uninjured rat.

Animals↗
PubMed1976

The relationship of skin temperatures of clothed adults to ambient temperature in a warm environment.

In forty-one apyrexial adult male patients, who were clothed in light-weight cotton pyjamas, mean skin temperature was determined and, simultaneously, ambient temperature and the temperature of air space under clothing were measured. Both mean skin temperature and the temperature of the air space under clothing showed a linear increase with ambient temperature. Heat loss by vapourization of water is known to have a curvilinear relationship to ambient temperature. Application of the temperature relationships obtained in this study to the vapourization curve indicates that clothing shifts the point of sharp upward inflection of the curve to the left; and, if ambient temperature is to be employed to predict the amount of cutaneous water loss in clothed individuals, the extent of this shift must be determined. The data obtained in the present study has been applied to studies of evaporative water loss in Lagos.

Adult↗