Biomedical subjects

E A Goldberg

Publications and source records attributed to E A Goldberg.

5 recordsLinked to original sources

PubMed2000

Advanced practice nursing in pediatric nephrology.

This article provides the nurse practitioner with a concise and accurate reference for the evaluation of children with hematuria, proteinuria, and hypertension. Although the incidence of these disorders in children is lower than in adults, they are not uncommon. The nurse practitioner must be able to accurately assess the results of a urinalysis and measure and interpret blood pressure readings in children. A discussion of when to refer children with signs and symptoms of serious disease; and how to educate patients and families in order to promote children's health is also provided.

Blood Pressure↗

PubMed1997

Physical assessment of children ages 1 to 10 years.

This is a two-part article on physical assessment of children with renal diseases. The first part of this article deals with the normal physical findings in children, ages 1 to 10 years. The article explores the four basic techniques of inspection, percussion, palpation, and auscultation according to body systems. The second part of this article discusses the physical findings that may be seen in children with renal diseases. The physical findings are reviewed according to body systems.

Age Factors↗

PubMed1997

Physical assessment of children ages 1 to 10 years with renal disease.

This article is a review of the many physical findings that one may encounter when examining a child with renal disease. It is the intention of this article to increase the knowledge base of the novice and heighten the awareness of advanced practitioners in relation to findings specific to infants and children.

Age Factors↗

PubMed1993

T-cell antigen receptor V beta subsets are not preferentially deleted in AIDS.

OBJECTIVE: Evidence for an HIV-1-associated superantigen (SAg) has been presented. Here we test whether targeted T cells are preferentially depleted in AIDS. DESIGN: The T cell antigen receptor (TCR) V beta repertoire was compared in 44 HIV+ hemophiliac patients and in 27 controls. METHODS: Eleven TCR V gene-specific monoclonal antibodies (MAb), representing approximately one-third of the V beta repertoire were used to measure T-cell numbers expressing V beta and V alpha genes in both the CD4 and the CD8 subsets by two-color immunofluorescence. RESULTS: The percentage of T cells expressing these V genes could be accurately quantitated in both the CD4 and the CD8 T-cell populations and at various clinical stages of disease progression. No preferential deletion of any particular V gene subsets was detected. CONCLUSION: CD4 T-cell depletion in AIDS is not V beta-selective.

Acquired Immunodeficiency Syndrome↗

PubMed1983

Morphological changes at the basement membrane during some tissue interactions in the integument.

Changes at the basement membrane have been reported at the time of tissue interactions during the development of a number of integumentary organs. During the development of vibrissa follicles of the mouse in vitro, gaps appeared in the lamina densa surrounding the dermal papilla at the time of the second, specific dermal message for follicle differentiation. Direct contacts between epithelial and mesenchymal cells were made through these gaps. This area has now been studied in vivo over the same period of follicle development. In addition, the epithelial part of the follicle has been separated from the dermal papilla by (i) enzyme treatment which destroys the lamina densa and (ii) chelating agents which leave the lamina densa attached to the dermal papilla. The resulting surfaces of epithelium and dermal papilla were examined by scanning and transmission electron microscopy. Small gaps first appeared in the lamina densa at the same substage of follicle development as in vitro and were present at the next substage. Processes from the dermal papilla mesenchyme cells traversed these gaps and made close contacts with the epithelial cells just prior to their differentiation into inner root sheath and hair. Instructive interaction through cell surfaces is suggested.

Animals↗