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Biomedical subjects

E A Iumatov

Publications and source records attributed to E A Iumatov.

At least 19 recordsLinked to original sources
PubMed2003

[Specific features of the structure of sleep and personality under the conditions of chronic emotional stress and methods of improving the adaptive abilities of man].

The results of a complex psychophysiological study of human sleep in the chronic stress condition are described. 20 patients with complaints of night sleep disturbances in the chronic stress condition and 10 healthy controls were examined by polysomnography. Profound changes of the quantitative and qualitative sleep parameters, mainly, related with the slow sleep phase, sleep delta characteristics and adaptive wakefulness mechanisms. The study demonstrated the effectiveness of improving the human adaptive parameters in the chronic stress conditions by using the drug and drugless therapy methods.

Adaptation, Psychological↗
PubMed2001

[Sleep stages after psychoemotional exposure: individuality-dependent changes].

Sleep stages were studied in healthy subjects with the aid of a battery of tests involving questionnaires, psycho-tests, motor tests, polysomnography, and cardiomonitoring. An induced psychoemotional tension was shown to change the 1st sleep stage, to decrease percentage of the 2nd stage of the slow-wave sleep, to redistribute the delta-sleep, and to suppress the REM sleep mechanism. The cerebro-visceral function of increasing the heart rate and its variability in night sleep was also affected. Patterns of the sleep structure changes depended on personality characteristics of the subjects. Thereupon, individual programs should be used in studies of psychoemotional stress effects upon the sleep pattern.

Adult↗
PubMed1997

[Methodology of functional theory systems in the design of devices for controlling human physiological functions].

The paper describes a basically new approach to solving the most urgent sociomedical problem--timely medical aid delivery in emergency acute vital dysfunctions in human beings. Based on the theory of functional systems, a new concept of medical equipment building for human life and health protection has been developed. The original guarded signalling devices referring to information domestic microprocessor techniques intended for daily individual continuous control and notification of the first objective signs of physiological dysfunctions are described.

Electronics, Medical↗
PubMed1995

[Neuromediator integration of emotional excitation and mechanisms of stress resistance].

The paper presents a study of the central neurochemical organization of negative emotional states changing into emotional stress. The neurotransmitter integration of negative emotional excitation wherein, in addition to classical neurotransmitters, endogenous peptides, such as substance P, prolactin, which are able to enhance emotional stress resistance serves as the basis of formation of a negative emotional state An idea of the central peptidergic mechanisms of limiting the development of emotional stress is formulated and experimentally evidenced within the current concept of the systemic organization of emotions.

Animals↗
PubMed1990

[Increasing resistance to emotional stress by endogenous peptide prolactin].

In real work we studied ability of endogenic peptide prolactin to raise the resistance of emotional stress under existing conditions of experimental model. Emotional stress was formed in the course of 5 days during 5 hours with fixation of groups of rats. All experimental animals were divided into three groups. The experiments showed the ability of the prolactin to raise the resistance of emotional stress.

Adrenal Glands↗
PubMed1988

[Hemodynamics in emotional responses and in emotional stress].

Negative emotional states induced with electrical stimulation of ventro-medial hypothalamus (VMH) or with behavioral conflicts were followed by vascular pressor responses tending to sum up. Positive emotional states were followed mainly by pressor-depressor vascular responses in animals. Obvious disorders of cardio-vascular functions occurred in experimental-emotional stress, vascular responses to the VMH stimulation being mostly of the pressor character. Changes in vascular tone were shown to play a major part in disturbances of the AP regulation in the immobilization stress, a progressing fall in the AP due to a sharp decrease in total peripheral resistance being the main reason of the animals' death. The resistance of cardio-vascular functions against emotional stress seems to be determined mainly by genetic mechanisms.

Adaptation, Physiological↗
PubMed1987

[Microiontophoretic study of the chemical sensitivity of neurons in the medial hypothalamus to substance P in rats].

Chemical sensitivity of the medial hypothalamic neurons to microiontophoretically applied substance P was studied in male immobilized Wistar rats. Over half of the neurons responding to the substance P by either increase or decrease of their firing rate. Neurons were found that changed their responses under repeated application of the peptide. The immobilization stress in rats seems to induce changes in chemical sensitivity of the medial hypothalamus neurons to substance P.

Action Potentials↗
PubMed1985

[Changes in the substance P content of the blood and hypothalamus during experimental emotional stress].

A study was made of the content of substance P in the blood and hypothalamus of Wistar rat brain in acute and chronic emotional stress and after intraperitoneal injection of substance P in a dose of 250 mg/kg. A possibility was demonstrated of inducing long-term changes in the content of substance P in the hypothalamus after a single injection. Exposure to a single 24-hour stress was followed by an increase in the substance P content in the hypothalamus.

Animals↗
PubMed1982

[Resistance factor in emotional stress in the brain of rats].

The authors review the results of extraction from the brain of emotional stress-resistant donor rats of fractions containing "factor" that causes the increased resistance to stress in recipient rats predisposed to stress. Brain homogenates of donor rats were subjected to thermal treatment, gel filtration on Sephadex G-15 and lyophilization. The fractions extracted are low-molecular weight, thermostable, resistant to pronase hydrolysis and significantly (P less than 0.05) increase the resistance of recipient rats to stress.

Animals↗
PubMed1981

[Changes in the neurochemical properties of midbrain reticular neurons during negative emotional responses].

Qualitative changes in responses of singly neurons of hte midbrain reticular formation to microionophoretically applied acetylcholine (ACh), serotonin (5-OT) and noradrenaline (NA) were revealed during stimulation of the "fear" centre in experiments on non-narcotized and non-immobilized rabbits. Approximately 50% of te units studied displayed changes which were manifested by occurrence or elimination of he responses or by reduction or activation of he responses to one or some agents. Afer ventromedial hypothalamic stimulation changes in chemical sensitivity of the reticular neurons were twice as often to NA and 5-OT than to ACh. A supposition is made that alteration in neurochemical properties of the central neurons can be one of the mechanisms of the development of negative emotional states.

Acetylcholine↗