Biomedical subjects
Publications and source records attributed to E A Ivanov.
Interaction between such components of photodynamic therapy as tumor, intact tissues, lighting and photosensitizers has been investigated. The efficacy of Photosense treatment was demonstrated in the experiments using transplantable tumors in Wistar rats. The photodynamic procedure both inhibited tumor process and stimulated immune system.
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In the past 12 years, there were 1.3- and 1.9-fold reductions in the total morbidity rates of tuberculosis and its spread, respectively. However, its morbidity among children showed 3-fold increases. The reduction rate of bacterial excretion became much slower in the past 4 years. Tuberculosis mortality rates tended to rise. At the moment of study, the basic tuberculosis epidemiological parameters were 1.3-1.5 times higher than those in the Russian Federation. At the same time there was a decrease in the efficiency of antituberculous work at all levels.
The dynamics in recurrences of pulmonary tuberculosis was analyzed in the areas of Yakutia. The social and clinical characteristics of patients with recurrences and their treatment outcomes are presented in the paper. Recurrences of pulmonary tuberculosis were found to occur more frequently in the areas having a poor epidemiological tuberculosis situation and among socially unprotected groups of the population. Under these conditions, recurrences may occur in 30 years or more after clinical cure of tuberculosis. To treat patients with recurrences in the area presents great difficulties.
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A total of 300 workers engaged in viscose industry were examined for leukocyte blast transformation, spontaneous and complement rosette-formation, blood serum immunoglobulins, bactericidal activity of blood serum, lysozyme titre, phagocytic activity of neutrophils, and the NBT test. The data obtained attest to the changes in the total nonspecific body responsiveness of the workers examined. The character and degree of the changes in cellular and humoral immunity were marked by cycles, depending on the workers' record. The changes in the total nonspecific responsiveness were found to persist for a long time even after discontinuation of the contact with carbon disulfide.
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The level of emotional stress depending on the power of motivation and the estimation by the subject of the probability (possibility) of goal achievement, largely influences the operator's skill performance (that of a pilot, controller, astronaut). A decrease in the emotional tonus leads to drowsiness, lack of vigilance, missing of significant signals, and to slower reactions. The extremely high stress level disorganizes the activity, complicates it with a trend toward untimely acts and reactions to the insignificant signals (false alarms). The best methods to monitor the degree of the operator's emotional state during his skill performance are the integral estimation of the changes in heart-rate and T-peak amplitude, as well as the analysis of spectral and intonational characteristics of the human voice during radio conversation. These methods were tested on paratroopers, pilots in civil aviation, and airport controllers.
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We here present a logical mathematical model for the visual perception of movement in man; it is based on the treatment of signals in the retina in relation to time and distance and on the statistical theory of the separation of signal from noise in the visual system. It shows good agreement with experimental results and has made it possible to determine the comparative level of internal noise of the visual system, the mean rate of spread of excitation from the photoreceptors along the surface of the retina, and many other characteristics.
The pathology of the motor analyser, originating in connection with local lesions of the brain may be studied by means of sensorimotor tracing method. By this parameter, localizations of the lesion produce dissimilar disturbances of the percentive-motor activity. Disorders in movement control were revealed in the case of disturbance of interhemispheric relations resulting from a lesion of the dominant hemisphere; as a result of disfunction of the frontal lobes, which led to disturbance of prognostication; due to disturbance of the "body scheme" and proprioreception disturbances.
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