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Biomedical subjects

E A Markova

Publications and source records attributed to E A Markova.

At least 19 recordsLinked to original sources

[Effect of prostaglandin E2 on the development of adrenaline-induced myocardiodystrophy].

In experiments on male rats it was established, that injection of prostaglandin E2 (PGE2) before the injection of adrenaline decrease essentially the activity of peroxidation of lipids in myocardium in comparison with animals which had only injection of adrenaline. Accordingly, pH is a factor, that limited a damage of myocardium on the development of adrenaline myocardiodystrophy.

Animals↗

[Characteristics of morphological changes in the myocardium of rats with different degrees of hereditary resistance to hypoxia during the development of adrenaline-induced myocardial dystrophy].

By means of polarizational microscopy method morphological changes of the cardiac muscle have been studied in highly-(HS) and poorly-stable (PS) rats to hypoxia 1 h and 1 day after injection of cardiotoxic dose of adrenaline (1.5 mg/kg of body mass). One hour after injection of adrenaline in PS animals the II-III stages of contractive myofibrillar changes are revealed, while in HS rats--the I-II stages. In 1 day in the myocardium of PS animals contractures of the III-IV degree are observed, more foci of clumping decay and myocytolysis than in HS rats. Severity of the morphological changes of the cardiac muscle after cardiotoxic dose of adrenaline essentially depends on the organism's reactivity.

Animals↗

[The quantity of immunoglobulins (A, G, M) in different forms of typhoid fever].

Results of determination of the quantitative content of immunoglobulins (IgA, IgG and IgM) demonstrated chronic typhoid carrier state to be a dynamic process characterized by high IgA and IgG indices which began to form as early as the acute period. A complex of clinico-laboratory indices permitted to detect the latent phase of the carrier state among the persons who sustained typhoid fever within the range of 30%; this confirmed the statement of a number of investigators put forward earlier that the true number of carriers was much greater than that recorded.

Acute Disease↗