Phosphate glass cement bone graft.
The objective of this study was to prepare cement-forming substances from phosphate glasses for use as a bone graft. The glass-forming system of CaO-SrO-Na2O-P2O5 was explored and ten phosphate glasses were prepared of varying compositions. Cements were made by reducing the glass to powders and reacting them with a water solution of calcium hydroxide or phosphoric acid. The cements were evaluated by X-ray diffraction, electron microscopy, density and porosity measurements, pH change during reaction and solubility in water. Because of the water solubilities of these cement materials, they may be useful as bone grafts containing drugs such as antibiotics which would be slowly released as the graft material degrades.
Biocompatible Materials↗