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Biomedical subjects

E A Pozhidaev

Publications and source records attributed to E A Pozhidaev.

14 recordsLinked to original sources

[Experimental substantiation of a precision technic of creating an interintestinal anastomosis in acute intestinal obstruction].

Two kinds of intestinal sutures performed with the use of a precision technique were investigated on models of acute intestinal obstruction. One-row (serous-muscular-submucosal) and two-row (serous-musculo-submucosal and submucosal-mucosal) sutures provide an exact layer-after-layer connection of the intestinal wall layers and a sufficient mechanical firmness of the anastomosis with little traumatization. The dynamics of microcirculation changes in the anastomosis zone was followed with the help of contact intraoperative biomicroscopy. Symptoms of the traumatic inflammation were cupped off within 5 days and changed by reparative processes.

Acute Disease↗

[Patterns characterizing different levels of animal organization].

The article deals with features of the regularities characterizing different levels of organization of the animal body. The cell is not only an integrated but also indivisible organic integrity which is due to the interaction of the nucleus and cytoplasm determining all sides of its vital activity. From this viewpoint the results of experiments on transplantation of the embryo cell nucleus into an enucleated egg of amphibia and the data on somatic hybridization are estimated. All processes of the cell life, their growth, multiplication and differentiation develop within the tissue system and are determined by the regularities of its development. The integrated system of the organism of a multicellular animal unites all the forms of integration of multi-step systemic pattern at different organization levels. Among different categories the systems of tissues and their interaction within the organ are most integrated. The regularities of the tissue development can not be brough to the regularities of the development of the anatomical structure of organs. The integration of cell elements in a tissue system and intertissue relations is the basis of all forms of interdependence in the cell development and the organism structure.

Animal Population Groups↗

[Morpho-functional changes in tissues surrounding a gunshot wound].

The authors studied the dynamics of changes of microcirculatory disorders in tissues surrounding the wound canal in experimental animals with gunshot injuries of the soft tissues of the thigh. Tissue radiometry and scanning were used. The damage was found to be regularly distributed in 4 zones of microcirculatory disorders differing also in morphological characteristics on a light and electron level: zone 1 of primary necrosis or traumatic destruction of tissues; zone 2 of secondary necrosis (forms on the 3rd day after the injury); zone 3 of reactive-destructive changes of tissues, which is the source of granulation tissue development (microcirculation in this zone is restored by the end of the 2nd week after the injury); zone 4 of reactive changes in the tissues with complete abatement of microcirculatory disorders by the end of the 1st week after the injury. The obtained data possess theoretical and practical significance.

Animals↗