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Biomedical subjects

E A Shipton

Publications and source records attributed to E A Shipton.

At least 55 records · Page 3Linked to original sources
PubMed1989

Low back pain and the post-laminectomy pain syndrome.

Back pain is one of the most common disorders seen in general practice. Patients with chronic low back pain form a large proportion of the work of any pain relief unit. The aetiology of low back pain and the post-laminectomy pain syndrome are briefly presented and treatment of the 'failed back surgery patient' and the patient with arachnoiditis are discussed.

Arachnoiditis↗
PubMed1987

A comparison of labetalol, acebutolol, and lidocaine for controlling the cardiovascular responses to endotracheal intubation for oral surgical procedures.

Arterial blood pressure and pulse rate changes following tracheal intubation were studied in 80 patients undergoing oral surgical procedures who received an etomidate/suxamethonium anesthetic induction sequence. Three treatment groups and a control group were used. Intravenous labetalol (1 mg/kg), acebutolol (0.25 mg/kg), lidocaine (2 mg/kg), and saline (1 ml), injected prior to anesthesia, were compared with respect to their effect on the hemodynamic consequences of direct laryngoscopy followed by the passage of an endotracheal tube. A pre-induction dose of labetalol was found to be more effective than acebutolol and lidocaine in attenuating the pressor response to instrumentation and intubation. Labetalol should prove most useful for those patients at risk from the transient hypertension and tachycardia following instrumentation and intubation.

Acebutolol↗
PubMed1986

Epidural fentanyl in the management of postoperative pain.

Epidural fentanyl (Sublimaze; Janssen) in the management of postoperative pain, with particular attention to efficacy and safety, was investigated. A treatment group (group 1) of 31 patients and a control group (group 2) of 30 patients were used. Group 1 received epidural fentanyl 100 micrograms postoperatively, while in the control group pain was treated with intramuscular pethidine 1.5 mg/kg 4-6-hourly as required during the 11 hours in the recovery room. Epidural fentanyl started working within 20 minutes and provided excellent analgesia for 8 hours or more postoperatively, comparable to repeated doses of intramuscular pethidine. Of the patients in group 1 13% experienced tolerable pruritus and the incidence of nausea and vomiting was small relative to that recorded in group 2.

Blood Gas Analysis↗
PubMed1985

Anaesthesia in connective tissue disorders.

Patients with the more common connective tissue disorders require surgical operations more frequently than has been realized. They may present the anaesthetist with many potential problems. A few minutes of careful questioning and examination pre-operatively may prevent a tragic situation. A history of drug therapy is essential pre-operative information, particularly since many of these patients will need augmentation or coverage with steroid drugs. The anaesthetist must be aware of the patient's general state of health and must search for evidence of pulmonary, cardiac or haematological abnormalities.

Anesthesia↗
PubMed1984

Effect of intramuscular atropine and glycopyrrolate on the cardiovascular response to tracheal intubation.

The effect of premedication with intramuscular atropine and glycopyrrolate on the cardiovascular changes resulting from the performance of laryngoscopy and tracheal intubation has been evaluated in two groups of 25 patients undergoing surgery. Neither atropine nor glycopyrrolate attenuated the hypertensive and tachycardic response to laryngoscopy and intubation; both significantly enhanced it (P less than 0,05).

Adolescent↗