Biomedical subjects
Publications and source records attributed to E A Shipton.
A 34-year-old White woman underwent surgery for the correction of bilateral ptosis. She had a known diagnosis of hypoparathyroidism following previous thyroidectomy, and was receiving replacement therapy. The peri-operative handling and the physiopathology and therapeutic management of hypoparathyroidism are discussed.
A 25-year-old White woman was admitted for exploratory thoracotomy for the removal of metastatic lesions from a hormonally active parathyroid carcinoma. The medical, intra-operative and anaesthetic implications are discussed.
Progress in the medical and social spheres has increased life expectancy by sustaining many who would otherwise have succumbed to congenital or acquired diseases. The number of aged and high-risk patients who require major surgical procedures for the cure or palliation of disease has therefore increased. The physiological and anatomical changes in and peri-operative evaluation of the geriatric patient are reviewed, as are the pharmacokinetics of drugs used in these patients.
Metabolic and biochemical studies of primary aldosteronism have led to major contributions to our understanding of the metabolic effects of mineralocorticoids and the control of aldosterone in man. Our current understanding of the syndrome and the progress that has been made in its differential diagnosis, its classification into various types and the localization and lateralization of a unilateral adenoma are reviewed. The perioperative anaesthetic management is presented and specific problems of importance to the anaesthetist are discussed.
Primary aldosteronism, when caused by an aldosterone-producing adenoma, is a surgically treatable condition. An operation was performed on a 44-year-old patient with this condition. The pre-operative preparation and anaesthetic management are presented. The specific problems of hypertension, hypokalaemia, hypokalaemic alkalosis and renal lesions, and their importance to the anaesthetist are discussed.
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Explore the source record for details and available documents.