PubMed Health⌕ Search

Biomedical subjects

E A Voth

Publications and source records attributed to E A Voth.

17 recordsLinked to original sources
PubMed1997

Medicinal applications of delta-9-tetrahydrocannabinol and marijuana.

The use of crude marijuana for herbal medicinal applications is now being widely discussed in both the medical and lay literature. Ballot initiatives in California and Arizona have recently made crude marijuana accessible to patients under certain circumstances. As medicinal applications of pure forms of delta-9-tetrahydrocannabinol (THC) and crude marijuana are being considered, the most promising uses of any form of THC are to counteract the nausea associated with cancer chemotherapy and to stimulate appetite. We evaluated the relevant research published between 1975 and 1996 on the medical applications, physical complications, and legal precedents for the use of pure THC or crude marijuana. Our review focused on the medical use of THC derivatives for nausea associated with cancer chemotherapy, glaucoma, stimulation of appetite, and spinal cord spasticity. Despite the toxicity of THC delivered in any form, evidence supports the selective use of pure THC preparations to treat nausea associated with cancer chemotherapy and to stimulate appetite. The evidence does not support the reclassification of crude marijuana as a prescribable medicine.

Appetite Stimulants↗
PubMed1997

Marijuana to prevent nausea and vomiting in cancer patients: a survey of clinical oncologists.

Marijuana, if rescheduled by the Drug Enforcement Agency, would be the only Food and Drug Administration (FDA)-approved drug to be administered by smoking. American physicians need timely, factual information about probable usage patterns and potential adverse effects of medical marijuana, and a factual complete review of the literature on the subject. We mailed a survey to 1,500 American clinical oncologists. Of particular interest was whether and how often in the past 24 months these physicians recommended smoked marijuana, synthetic tetrahydrocannabinol, or 5-HT3 (serotonin) antagonists (ondansetron [Zofran], granisetron [Kytril]) for their patients. We also inquired whether and how often the oncologists would prescribe marijuana in the form of cigarettes, were it to be FDA-approved. Completed surveys were received from 1,122 (75%) of the oncologists. The percentages of oncologists who prescribed or recommended selected antiemetics more than five times between 1992 and 1994 were 98% for 5-HT, antagonists, 6% for dronabinol (Marinol), and 1% for smoked marijuana. We also found that 332 (30%) of the oncologist-respondents to this nationwide survey supported rescheduling of marijuana for medical purposes; however, two thirds (67%) of the 332 respondents who were in favor of rescheduling estimated that they would write less than one prescription per month for marijuana cigarettes. A comprehensive literature review failed to provide persuasive evidence to recommend marijuana as a needed antiemetic medicine.

Attitude of Health Personnel↗
PubMed1995

Drug legalization, harm reduction, and drug policy.

The current U.S. policy options on drug use are reviewed in the context of the history of drug policy in the United States. A restrictive drug policy is a deterrent to drug use and helps reduce drug-related costs and societal problems. Although legalization or decriminalization of drugs might reduce some of the legal consequences of drug use, increased drug use would result in harmful consequences.

Costs and Cost Analysis↗
PubMed1994

The war on drugs.

Explore the source record for details and available documents.

Adolescent↗
PubMed1991

Responsible prescribing of controlled substances.

One-third of the disciplinary actions against physicians in 1990 involved prescriptions for controlled or abusable drugs. Problems involving the prescribing of controlled medications may occur because of overdose, dependence or use by known drug abusers. A common problem facing the physician is the identification of potential overdose victims and addicted patients. Requests for early prescription refills, claims of lost prescriptions, frequent after-hours calls and patient intolerance to nonnarcotic pain-relieving drugs should raise suspicions of drug abuse.

Drug Overdose↗