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Biomedical subjects

E A Wells

Publications and source records attributed to E A Wells.

At least 37 records · Page 2Linked to original sources
PubMed1989

Skills training for drug abusers: generalization, maintenance, and effects on drug use.

This study reports on the follow-up data for the treatment of drug abuse (Hawkins, Catalano, & Wells, 1986). In the original study, 130 clients in the reentry phase of residential drug treatment programs were randomly assigned to a control group (n = 60) or to a 10-week supplemental behavioral skills training course (n = 70). Eight-two percent of the sample was male, and 75% was White. Subjects' ages ranged from 15 to 55 years, though the majority (71%) were in their twenties. A role-play test assessing skill levels was administered as a pretest, following the 10-week skill training course, and again at 6 and 12 months as follow-ups. Although skills decayed slightly over time, the skill levels of experimental subjects were higher than the control group 12 months after training. Generalization of skills to role-play situations for which no training had been received was also found. However, with the exceptions of marijuana and amphetamine use, skill training did not affect drug use after treatment.

Behavior Therapy↗
PubMed1989

Delinquents and drug use: a model program for community reintegration.

Evidence indicates that serious and persistent delinquency and the frequent use of illicit drugs emerge from common etiological roots. This suggests that treatment efforts which target risk factors of adolescent drug use and crime may be effective in preventing subsequent antisocial behavior. This paper describes Project ADAPT, a treatment program for juvenile delinquents based on the Social Development Model, which integrates this knowledge of risk factors. Project ADAPT is a 3 1/2-year demonstration project which combines behavioral skill training, supportive network development, and involvement in prosocial activities to facilitate the community reentry of youths following placement in a Washington state correctional facility.

Adolescent↗
PubMed1988

Choosing drug use measures for treatment outcome studies. I. The influence of measurement approach on treatment results.

Drug use is measured in a number of different ways in drug treatment outcome studies. Different measures of outcome may yield different results, making comparison across studies difficult. The utility, sensitivity, and level of measurement of five categories of measures are reviewed. It is suggested that research focus on examining the properties of existing drug use measures, on developing methods of evaluating timing and sequence in the relapse process, and on standardizing measurement approaches across studies.

Follow-Up Studies↗
PubMed1988

Choosing drug use measures for treatment outcome studies. II. Timing baseline and follow-up measurement.

The use of different approaches to measurement in drug abuse treatment outcome studies has resulted in a lack of comparability across studies. This paper reviews different approaches to timing of baseline and follow-up periods and to dealing with time periods during which follow-up subjects are not "at risk" for drug use. Length and timing of baseline and follow-up periods are considered as well as periods of time within which specific drug use outcomes are measured. It is suggested that research focus on describing the natural course of drug use both prior to and following treatment, in order to determine the most appropriate length and timing of follow-up periods. It is recommended that investigators report drug use data from both "at risk" and "not at risk" periods, and that they choose methods of controlling for time "at risk" which do not eliminate important drug use data from analyses.

Follow-Up Studies↗
PubMed1982

Trypanosoma vivax in Colombia: interpretation of field results.

The use of the indirect fluorescent antibody test and complementary blood smear examinations in Colombia has shown that Trypanosoma vivax infections of cattle may be considered to be distributed throughout the tropical and subtropical areas of the country. However within this distribution the prevalence showed wide variations between herds and localised epidemic situations could occur at the herd and village level. the examination of sequential serum samples from 2 localities has given additional information on incidence and on transmission patterns.

Animals↗
PubMed1981

Mammalian wildlife diseases as hazards to man and livestock in an area of the Llanos Orientales of Colombia.

Development of the LLanos Orientales of Colombia, and access to underdeveloped areas in the Llanos, may create disease hazards to man and domestic animals or introduce exotic pathogens, creating reservoirs of infection for domestic animals and acting as limiting factors on the native wild species. A survey of wild animals common to the Llanos revealed a number of parasites indigenous to the area. A total total of 59 mammalian species, representing eight orders were examined. Haematozoa were represented by Trypanosoma cruzi, T. evansi and T. rangeli. Eight species of ticks were found: Amblyomma cajennense, A. auricularium, A. rotundatum, A. maculatum, A. longirostre, A. pacae, Ixodes luciae and Boophilus microplus. Four species of fleas were found: Rhopalopsyllus lugubris lugubris, R. australis tupinus, R. cacicus saevus and Polygenis klagesi samuelis. A species of Echinococcus was commonly found in Cuniculus paca. Serologic titers and/or isolations of pathogenic viral and bacterial agents generally indicated that the wildlife population had not been exposed to the diseases common to the domestic population. A low prevalence of titers to Venezuelan equine encephalomyelitis was found in Cebus apella and Proechimys sp. Neutralizing antibodies to Group B viruses were found in Proechimys sp., Coendor sp. and Nectomys squamipes. Antibodies to Group C viruses were found in Proechimys sp. Serologic titers to Leptospira sejroe and L. tarassovi were found in Proechimys sp. and Didelphis marsupialis. L. tarassovi was isolated from Proechimys sp. Titers to Brucella were not found in 1964 animals. The significance of these findings are discussed.

Animal Diseases↗
PubMed1979

Polycystic echinococcosis in Colombia: the larval cestodes in infected rodents.

Described are the characteristics of the polycystic larval cestodes found in an endemic area of echinococcosis in the Easter Plains of Colombia and the tissue reaction evoked in infected rodents. Of 848 free-ranging animals examined, polycystic hydatids were found in 44/93 Cuniculus paca and 1/369 Proechimys sp. None of 20 Dasyprocta fuliginosa examined was infected, but hunters provided a heart with hydatid cysts and information about two additional animals with infected livers. Recognition of an endemic area of polycystic echinococcosis provides a means to investigate the life cycle of the parasites and to study the histogenesis of the larval cestodes in susceptible laboratory animals.

Animals↗
PubMed1976

The capybara (Hydrochoerus hydrochaeris) as a reservoir host for Trypanosoma evansi.

Discovery of two ill horses and three dogs naturally infected with Trypanosoma evansi near an experimental station in the Eastern Plains of Colombia led to a search for reservoir hosts of the parasite. Infection was detected in 8/33 healthy capybaras (Hydrochoerus hydrochaeris), none of the remaining 14 horses, and none of 32 Zebu cattle (Bos indicus), 18 paca (Cuniculus paca) and 20 spiny rats (Proechimys sp.). Contrary to common opinion, the results indicated a carrier state in the capybara. Diagnosis was based on morphology, behaviour in albino rats, and pathogenicity and host range in domestic animals.

Animals↗