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Biomedical subjects

E A Weymuller

Publications and source records attributed to E A Weymuller.

At least 55 records · Page 3Linked to original sources
PubMed1985

Laryngeal injury in a dog model of prolonged endotracheal intubation.

Using a dog model of prolonged translaryngeal intubation, the authors studied laryngeal injury. Segments of 10.7 mm diameter endotracheal tube were sutured in place in the larynges of anesthetized animals, and the animals were allowed to awaken and the tubes left in place for periods of 24 h to 84 days in a total of 13 dogs. Each animal's larynx was studied endoscopically at weekly intervals and at the time of death. Both endoscopic and postmortem examination revealed erythematous laryngeal mucosa at 24 h and severe mucosal ulceration by 1 week. Microscopic examination revealed mucosal inflammation at 24 h with loss of mucosal architecture by 1 week. In several animals intubated 1 week or longer, inflammatory infiltrates were present in the arytenoid cartilage. While damage was generally severe by 1 week, it did not tend to become more severe after that time. Between week 1 and week 12, there was no significant correlation of the severity of laryngeal injury with the duration of endotracheal intubation. The results suggest that duration alone may not be a factor in laryngeal injury after the first week of intubation.

Animals↗
PubMed1985

Complications of bacterial infection of the ears, paranasal sinuses, and oropharynx in adults.

Early recognition of potentially fatal complications of bacterial infections of the ears, sinuses, and pharynx is important for successful therapy. The clinical presentations of these infections are reviewed in this article, and the approach to initial diagnostic tests is outlined. Treatment recommendations are briefly discussed, with emphasis placed on early antibiotic therapy and indications for consultations from surgical colleagues.

Adult↗
PubMed1984

The cheek-neck rotation flap for closure of temporozygomatic-cheek wounds.

The head and neck surgeon is often consulted for evaluation and treatment of traumatic or neoplastic lesions of the lateral aspect of the face. Large malignant cutaneous lesions may require excision with wide margins, often parotidectomy, and possibly neck dissection. Traumatic lesions may involve notable soft-tissue loss, and parotid, facial nerve, or mandibular injury. Management of such planned or unplanned wounds challenges the surgeon due to the magnitude of the soft-tissue defect, cosmetic and functional considerations, and the need for soft-tissue protection and nourishment of repaired structures. Primary reconstruction with a large cheek-neck rotation flap provides the advantages of reliability, simplicity, excellent exposure, vital-structure protection, superior aesthetic results, and eliminates the need for a second operative site to harvest skin grafts or distant flaps. Four illustrative cases are reported, with a discussion to address parotid metastases from carcinoma of the lateral aspect of the face and initial treatment of shotgun injuries to the face.

Adolescent↗
PubMed1983

Aspiration cytology: an efficient and cost-effective modality.

Aspiration cytology is under-utilized in the evaluation of neck masses. This paper establishes the historical perspectives for the procedure which document its accuracy and safety. The discussion emphasizes the appropriate application of the technique and the strong arguments for its cost effective use as a primary diagnostic modality in evaluation of head and neck mass lesions.

Aged↗
PubMed1982

Studies in transtracheal ventilation catheters.

A study was undertaken to assess the applicability of transtracheal ventilation in the instance of total upper airway obstruction. The effect of transtracheal jet ventilation through a variety of inflow catheters in the dog was studied. Arterial blood gas values, intratracheal pressure and minute ventilation were compared. Deflation of the airway through an array of outflow needles was independently assessed. Hypercapnia, decreased minute ventilation, and prolonged inspiratory and expiratory durations impaired use of the smallest catheters. A dual-lumen needle, to provide exclusive respiratory access and support was then designed based on the preliminary data. Prolonged transtracheal jet ventilation with a totally obstructed upper airway was successfully conducted in a live canine subject. A review of the literature is presented.

Airway Obstruction↗
PubMed1981

Epilepsy complicated by sleep apnea.

A patient with a medically intractable seizure disorder was found to suffer sleep apnea as well. Treating the sleep apnea with permanent tracheostomy improved his generalized seizures. Although this combination of neurological disorders is probably rare, it should be considered if a suggestive history is obtained.

Adult↗
PubMed1981

Assessment of cobalt 57 tagged bleomycin as a clinical aid in staging of head and neck carcinoma.

Critical assessment of head and neck cancer with respect to staging has, on occasion, been disappointingly ineffective. We have attempted to correlate the incidence of measureable uptake of cobalt 57 tagged bleomycin by primary squamous cell carcinoma and metastatic cervical lymph nodes. Forty-six cases have been evaluated with respect to histopathological confirmation of the suspected metastatic disease. We have found that this diagnostic measure increases our acumen in staging of head and neck cancer. The relevance of the Co-Bleo scans as a diagnostic aid is reported in 46 cases. Malignant tumors greater than 2 cm in size appear to demonstrate active uptake of the imaging agent. Small tumor size and excess background radioactivity contribute to the false-negatives (17%). Inflammatory conditions or benign tumors of the salivary apparatus may result in minimal uptake, thus, a false-positive result (10%). An increase in the radioactivity of the Co-Bleo may enhance the benefits of this procedure in the search for an undiagnosed primary, as well as undiagnosed local or distant metastases.

Adult↗
PubMed1980

A comparison of treatment modalities in carcinoma of the maxillary antrum.

Sixty-two patients with carcinoma of the maxillary antrum are observed to define symptoms, physical findings, and radiologic findings suggestive of a poor prognosis. Using these poor prognostic indicators, the cases are retrospectively analyzed according to the various treatment modalities that were used. It is concluded from the accumulated data that raesection of the orbital contents can be avoided in selected patients with T3 and T4 carcinoma of the paranasal sinuses.

Adenocarcinoma↗
PubMed1980

Objective assessment of laryngectomized patients with surgical reconstruction.

The assessment of worth of the neoglottic procedure has been, for the most part, subjective in nature. Evaluation by means of sequential objective measures has been developed. The following procedures are employed in our assessment: transcription intelligibility by judges unfamiliar with the passage; rate of speech; relative intensity range; intratracheal air pressure; continuous speech per breath; functional communication profile; weight status; contrast swallow study; swallow-aspiration diary; and tumor status. Data from a patient with a Staffieri neoglottis procedure illustrate the method.

Deglutition↗
PubMed1980

Evaluation of neck masses.

This paper presents the general principles for evaluation of a neck mass. Included are a differential diagnosis according to patient age and location of the neck mass, and a differential diagnosis of neck masses related to the variety of anatomic structures found in the neck. Also included is a detailed discussion of the history and physical examination appropriate for evaluation of neck masses. Subsequently, the various tests which may be appropriately applied to the evaluation of neck masses are described. Neck masses require a thorough and thoughtful evaluation; a hasty decision for open biopsy is inadvisable. When any significant question regarding diagnosis and therapy arises, the patient should be referred to a competent head and neck specialist.

Adolescent↗