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Biomedical subjects

E A Zakhariia

Publications and source records attributed to E A Zakhariia.

At least 19 recordsLinked to original sources

[Enzyme activity in the blood serum as a criterion of the severity of acute cholecystopancreatitis].

The activity of lactate dehydrogenase, gamma-glutamyltranspeptidase, alkaline phosphatase, 1-antitrypsin was studied in 30 patients with acute cholecystopancreatitis of different severity grades. It was found that changes of activity of these enzymes depending on the severity of the disease may be considered as a criterion of regression of the inflammatory changes in the biliary-pancreatic zone as well as a criterion of recovery.

Acute Disease↗

[Coagulation properties of the thrombocytes in macro-focal myocardial infarct].

Platelet coagulative and fibrinolytic activities were studied in 37 patients with large myocardial infarction. Plasma samples rich for platelets (with the standard platelet level) and with low platelet counts were analyzed. A lowered coagulative activity of the platelets was revealed in such patients, parallelled by loss of these cells' ability to enhance fibrinolysis. These shifts are particularly marked in the first days of the illness.

Adult↗

[The diagnosis and treatment of patients with acute intermittent porphyria].

Four patients with acute intermittent porphyria (AIP) were treated and followed-up. It was established that in AIP urinary pigments have specific absorption spectra in the visible light range. Clinical manifestation and the severity of the disease course correlated with the amount of excretion of copro- and uroporphyrin and their characteristic spectrum of light absorption. It is concluded that of significance in the AIP pathogenesis is the level of formation of copro- and uroporphyrin isomers which may directly effect the nervous tissue and clinical manifestations of AIP. It is recommended to use plasmapheresis in biohemosorption by means of extracorporeal donor spleen.

Acute Disease↗

[Experience in attracting co-workers at a department of clinical laboratory diagnosis to diagnostic and therapeutic work].

The experience gained by the Lvov City Clinical Hospital for Emergencies evidences the usefulness of participation of the workers of clinical diagnosis chairs in practical diagnostic and therapeutic work, for it considerably reduces the number of diagnostic errors. The authors consider such cooperation between practicing physicians and laboratory workers (many of them are not physicians) very useful and recommend to change the system of training in laboratory diagnosis at specialized and advanced training courses so that the number of physicians working at clinical diagnosis laboratories be increased.

Laboratories, Hospital↗

[A simplified method of determining the aggregation and disaggregation of thrombocytes].

The authors have simplified the technique developed by Born (1962) and Howard (1973) for measuring the platelet aggregation and disaggregation. The method determines the platelet aggregation index, aggregation rate, platelet aggregation summary index, and platelet disaggregation index. The suggested procedure is informative, simple and available for any clinical diagnostic laboratory.

Humans↗

[Autocoagulogram indices of patients with ischemic heart disease].

Data are presented of an investigation of the coagulation activity of the blood plasma and whole erythrocytes carried by means of autocoagulography in 84 patients in the dynamics of ischemic heart disease. The patients showed an increased coagulation activity of the blood plasma and an insufficient compensation by erythrocytes in the course of the disease. Complex treatment including heparin did not change the procoagulant activity of erythrocytes.

Adult↗