Biomedical subjects

E Aagaard

Publications and source records attributed to E Aagaard.

5 recordsLinked to original sources

PubMed1998

Evaluation of trismus, bite force, and pressure algometry after third molar surgery: a placebo-controlled study of ibuprofen.

PURPOSE: This study evaluated trismus, bite force, and pressure algometry as measures of analgesic efficacy after third molar removal. PATIENTS AND METHODS: Fifty-seven patients (36 females and 21 males) developed at least moderate pain after surgical removal of a mandibular third molar and were given either ibuprofen, 400 mg (n = 26), or placebo (n = 31) in a double-blind study. Pain intensity and pain relief were rated on a five-point verbal rating scale during the 4-hour study period. Recordings of trismus, bilateral pressure pain detection and tolerance thresholds, and bite force were performed before surgery, at medication, and hourly for 4 hours. Changes in the functional variables were calculated as percent change from baseline (before surgery). RESULTS: The pain intensity and pain relief ratings showed significant differences between the ibuprofen- and placebo-treated patients in the 4-hour study period. The changes in trismus, bite force, and pressure pain thresholds were in accordance with these pain ratings. Pressure pain detection threshold on the operated side was significantly lower in the placebo-treated patients compared with the ibuprofen-treated patients 2 and 3 hours after medication, whereas pressure tolerance threshold showed a significant difference after 2 hours. Bite force on the operated side was significantly less reduced 3 hours after treatment with ibuprofen when compared with placebo. CONCLUSIONS: The functional measures used support the results obtained by rating of pain intensity and pain relief, and could be of value as measures of the efficacy of an analgesic to reduce functional impairment caused by postoperative pain.

Adolescent↗

PubMed1998

Evaluation of a new radiographic technique: outcome following removal of mandibular third molars.

OBJECTIVE: To compare the effect on outcome of third molar removal of pre-operative radiographic assessment by two different techniques. METHODS: Two hundred and sixty three patients were allocated prior to surgery to one of two diagnostic groups. One hundred and thirty-seven were examined by the Scanora and 126 by a panoramic plus three intra-oral radiographs. Ten oral surgeons recorded their operating time in minutes. Postoperative pain was recorded 4 h after the operation by the patients on a Visual Analog Scale (VAS). The following clinical parameters were recorded at the 1-week postoperative examination: alveolitis, bleeding, and swelling related to the operation area, and any other complications such as paresthesia, nausea and trismus. RESULTS: There was no significant difference in operation time between the two groups of patients (t-test; P > 0.82) nor in the frequency of immediate postoperative pain (chi 2-test; P > 0.5). There were no statistically significant differences in pain score between patients who experienced pain in the two groups (P = 0.10). Sixty-four patients experienced one or more postoperative complications, but the differences between the two groups were not statistically significant (chi 2-test; P > 0.05). There were no significant differences between the surgeons in the number of patients they operated on who experienced pain (chi 2-test; P = 0.18) or who developed complications (chi 2-test; P = 0.27). CONCLUSION: There are no adverse effects on the rate of postoperative complications when surgeons with little experience with it base their diagnosis and treatment plan on Scanora compared with conventional radiography.

Adult↗

PubMed1998

Evaluation of a new radiographic technique: diagnostic accuracy for mandibular third molars.

OBJECTIVE: To compare the accuracy of Scanora with that of traditional panoramic and intra-oral radiography for the assessment of impacted mandibular third molars. METHODS: Two hundred and fifty-four patients referred for removal of impacted or partly erupted third molars were randomly allocated to one of two groups; 133 were examined by the Scanora system and 121 by a panoramic plus a series of three intra-oral radiographs. The radiographs were read by a trained oral radiologist and her diagnoses validated against the surgeons' findings at operation. RESULTS: There was agreement about the state of tooth eruption in 71.4% of Scanora and 74.4% of conventional examinations and about tooth position in 77.2 and 69.7% respectively (P < 0.05). The number of roots was assessed more accurately by Scanora (82.7% agreement) than by conventional (71% agreement) examination (P < 0.05). There was agreement about the root morphology in 70.4% of Scanora and 62.4% of conventional examinations. In 12% of the patients, the roots were in very close contact with the canal determined by the surgeon. In approximately 50% of these cases, the close contact to the canal was found by radiography with no significant differences between the methods. CONCLUSION: The Scanora method was more accurate when validated against the surgeons' findings for the position and number of roots of ectopic mandibular third molars while both methods were equally accurate in demonstrating the relation between the roots and the inferior alveolar nerve.

Adolescent↗

PubMed1991

Performance for obtaining maximal gain from a program for digital subtraction radiography.

The aim of this study was to evaluate the effect on subtraction image quality of number of a) gray shades sampled during camera recording, and b) reference points positioned in the two images to be subtracted. Intraoral radiographs were obtained in each of 12 patients, one at 0 degrees and one at 15 degrees horizontal angulation in a standardized recording procedure. The radiographs were videorecorded twice sampling 1) 160-180 and 2) 200-220 shades of gray. The 0 degrees radiographic image was digitally copied. Subtractions were performed between the identical (0 degrees/0 degrees) and the non-identical (0 degrees/15 degrees) radiographs from both gray shade samples after positioning 5, 10, 15, and 20 reference points, respectively, in each of the images to be subtracted. The standard deviation in the subtraction image histogram was used as the test parameter for image quality. No differences existed between image quality obtained from the radiographs sampled using 160-180 and 200-220 shades of gray (P greater than 0.05). The standard deviation fell continuously, the more reference points were positioned in the images. For the 0 degrees/0 degrees images the difference was statistically significant between the 5 and 10 point images (P = 0.045) while for the 0 degrees/15 degrees images differences existed between 5 and 10 point images (P = 0.077) and the 10 and 15 point images (P = 0.048). The precision of reference point positioning as evaluated in the two identical images was satisfactory, the divergence being on average 1.4 pixels.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

PubMed1989

A new case with hereditary xanthinuria: response to exercise.

The concentration of purines in plasma and urine from a 37-yr-old healthy man with a very low plasma urate concentration was measured by HPLC. A persistent increase in xanthine and a slight elevation of hypoxanthine was found. The metabolic response to intensive treadmill running and long distance running was investigated. The hypoxanthine concentration increased to about the same level as in healthy controls, but the elimination from plasma was considerably slower. The high xanthine level was practically unchanged by exercise.

Adult↗