Biomedical subjects
Publications and source records attributed to E Abdel-Sattar.
The chloroform fraction of the defatted ethanol extract from the aerial parts of Caralluma penicillata yielded three C-15 oxypregnane glycosides, penicillosides A-C. Their structures were established by a combination of spectroscopic methods.
From the chloroformic extract of the resinous exudate of the stems of Eucalyptus maculata, four phenolic constituents have been isolated. A new di-cinnamic acid glucose ester was isolated, in addition to cinnamic acid, 7-methyl aromadendrin and sakuranetin. The isolated compounds were elucidated using UV, IR, 1D and 2D NMR and MS.
The cis-isomer (2) of the previously isolated parthenolid-9-one (1) was isolated from Anvillea garcinii and the structures and relative stereochemistries of both were determined from NMR data in combination with single-crystal X-ray analysis. In vitro cytotoxicity and in vivo antitumor activity for both compounds are reported.
The aerial parts of Caralluma russeliana yielded four new pregnane glycosides, russeliosides A-D (1-4), in addition to a known flavone glycoside, luteolin 4'-O-beta-D-neohesperidoside. The structures of compounds 1-4 were elucidated using a combination of spectroscopic methods.
The aerial parts of Vernonia cinerascens, collected in Saudi Arabia, yielded a new hirsutinolide, together with three known lactones. The structure of the new compound was elucidated using, 1H NMR, 13C NMR, 1H-1H COSY, 1H-13C HETCOR and HMBC.
The aerial parts of Teucrium yemense yielded two iridoid glycosides. Their structures were elucidated by spectral means as teucardosid and 8-O-acetylharpagid.