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Biomedical subjects

E Aldor

Publications and source records attributed to E Aldor.

35 records · Page 2Linked to original sources

[Negative and positive imaging of myocardial infarct].

In 41 patients myocardial scintigrams were performed using 2 mCi 201T1 and 15 mCi 99mTc-diphosphate. 9 healthy persons showed no myocardial imaging with 99mTc-diphosphate and normal 201T1 scintigrams. Transmural infarctions could be documented by both isotopes, excepted lateral and apical infarctions which could only be shown by means of 99mTc-diphosphate. Non-transmural infarctions could not be identified, myocardial scars however--as was to be expected--showed only activity defects within the 201T1 scintigrams without corresponding images in the 99mTc-diphosphate scans. One patient with severe coronary heart disease showed diffuse diphosphate uptake all over the myocardium with normal 201T1 scintigram. The combined myocardial scintigraphy provides a better diagnosis, enabling an improved localisation of infarction and avoiding misinterpretations.

Humans↗

[Propafenon, a new anti-arrhythmic drug (author's transl)].

Propafenon, at an initial oral dose of 900 mg, proved an effective anti-arrhythmic drug in 34 patients with frequent ventricular and(or) supraventricular extrasystoles at rest. Long-term ECG monitoring of seven patients revealed that this effect lasted about eight hours. It can be maintained by an oral dose of 300 mg propafenon at eight-hourly intervals, as demonstrated in 21 further patients. Rapid anti-arrhythmic action was achieved in six acute cases with 1.0-1.5 mg propafenon per kg body weight by quick infusion, and lasted for one to one-and-a-half hours. In such cases the drug should, therefore, be given synchronously by the oral route. Side effects related to the gastrointestinal tract, sinus automatism as well as atrio-ventricular and intraventricular conduction, but in no case were very serious.

Administration, Oral↗

[Alteration of coronary blood flow after injection of a contrast medium (author's transl)].

The injection of with different, energetic separable radioactive isotope labelled particles in the same coronary artery before and short after the injection of a contrast medium reveals in many cases variable scintigraphic pictures. The temporary vasodilatation caused by the contrast medium produces in presence of a coronary stenosis a disturbance of the regional blood flow. Thereby we find in the poststenotic myocardial area a transient ischemia, bringing about a decrease of the activity at the scintigram. As this transient ischemia is only demonstrable with a hemodynamic effective stenosis, in such cases a good effect of coronary surgery can be expected. On the other hand, in the presence of effective stenoses in all three coronary branches, in the double-scintigram alterations of the perfusion can be missed, showing the same scintigraphic picture as with normal coronary arteries.

Contrast Media↗

[Myocardial blood flow in actively employed coronary cases].

In the course of coronary angiographies the blood flow of the right and left coronary artery was determined by the 133Xe lavage method in 89 patients with coronary heart disease. There was a statistically significant difference between the flow values of the LCA and RCA, while there was none between the blood flow values of blue- and white-collar workers suffering from coronary artery disease. Also a significantly better blood circulation of the right as well as of the left coronary artery was found in female employees in comparison to male employees.

Adult↗