PubMed Health⌕ Search

Biomedical subjects

E Allegra

Publications and source records attributed to E Allegra.

11 recordsLinked to original sources
PubMed1992

Cytogenetic alterations in laryngeal carcinomas.

The purpose of this study was to determine the most frequent chromosomal abnormalities in laryngeal carcinomas. Biopsy specimens of surgical resections from laryngeal squamous cell carcinomas from 15 patients representing different degrees of histologic differentiation were analyzed in short-term culture. Nine of the 15 tumors were hypodiploid with 41 to 45 chromosomes, and four of the 15 tumors were polyploid with more than 50 chromosomes. The most frequent chromosomal alterations we noted included deletion of the short arm of chromosome 3 in 60%, monosomy of chromosome 11 in 30%, and inversions of chromosome 9 and 16 that were present in 20% of the cases.

Carcinoma, Squamous Cell↗
PubMed1992

[Crohn disease in pregnancy. Considerations on and discussion of a clinical case].

Crohn's disease with acute abdomen in pregnancy is described. The Authors evaluate Crohn's disease together with the diagnostic, prognostic and therapeutic problems and relationships between this disease and pregnancy. They conclude as underlining the rarity of Crohn's disease beginning in pregnancy and so the importance of symptoms related to this disease in fertile age woman to make diagnosis and therapy before pregnancy.

Abdomen, Acute↗
PubMed1989

In vitro short-term chemosensitivity test in head and neck tumors.

A new method to test the sensitivity of human tumor cells has been developed. A suspension of mechanically dissociated tumor cells is kept in continuous incubation for 24h, in cultures with antineoplastic agents. Drug induced cell cycle perturbations are monitored by flow cytometric computer analysis and DNA distributions of the cells stained with propidium iodide are expressed in percentage. The test is used in 15 head and neck human solid tumors. The drugs tested were: VCR, EpiDx, CDDP, MTX, 5-FU, CPM, BLM. The results obtained reveal that tumor sensitivity varies independently from the stage and malignity grading. Therapeutic combinations are assigned by selecting the drugs on the basis of the individual in vitro response.

Aged↗
PubMed1981

An approach to chemical characterization of human placental extracts: proteins, peptides, and amino acids analyses.

A procedure is described for characterization of the proteinic, peptidic, and amino-acidic components of human placental extracts. Four different preparations were analyzed. The first was an extract prepared in our laboratory from fresh on-term placenta. The other three were commercial products obtained by different procedures including autolysis and sterilization. The patterns given by each type of preparation are reproducible and characteristic.

Amino Acids↗