PubMed Health⌕ Search

Biomedical subjects

E Altmann

Publications and source records attributed to E Altmann.

53 records · Page 3Linked to original sources
PubMed1991

[Experiences with the Günther filter].

In the investigation 17 patients with lung embolism being cared for with a Guenther-filter were post-observed during a period up to two years. Early complications after the implantation of the Guenther-filter did not occur in any case. Late complications after the implantation of the Guenther-filter were dislocations, deformations of the filter and breaks of the spokes. In the result of the post-observation the Guenther-filter application despite its easy handling should be regarded very critically.

Aged↗
PubMed1990

[Results of using EEG and carotid angiography for evaluating cerebrovascular insufficiency].

In the cerebrovascular disease the EEG can give references at localisation, extension and course. The ability of statement is increased by methods of provocation and activation. On 35 patients with cerebrovascular insufficiency can be indicated that there are good correlations between changes on the large cerebral supply vessels and changes of the EEG, in particular in the carotid pressure trial.

Adolescent↗
PubMed1990

[Doppler sonography in the diagnosis of extracranial vascular changes].

On account of cerebrovascular insufficiencies or asymptomatic vascular noises which had taken place 45 patients were examined by means of Doppler sonography and after this by means of angiography. The judgement of the common carotid artery, the internal and external carotid arteries, the vertebral artery, the subclavian artery and the supratrochlear artery were involved into the ultrasound investigation. The sensitivity of the supratrochlear compression test was 50% in the diagnosis of high-degree stenoses and occlusions of the internal carotid artery, whereas the sensitivity of the complete ultrasound investigation way about 80%. The advantages and disadvantages of the ultrasound Doppler sonography investigation are discussed.

Adult↗
PubMed1988

Conformational studies on host-guest peptides containing chiral alpha-methyl-alpha-amino acids. Comparison of the helix-inducing potential of alpha-aminoisobutyric acid, (S)-2-ethylalanine and (S)-2-methylserine.

The conformational behaviour of host-guest peptides of the type Ac-Ala-Xxx-Ala-Ala-Xxx-Ala-Ala-Xxx-Ala-Ala-NH-PEGM (Xxx = alpha-aminoisobutyric acid (Aib), (S)-2-ethylalanine ((S)-Iva), (S)-2-methylserine ((S)-alpha-MeSer)) has been studied by CD spectroscopy in CF3CH2OH, CH3OH, and water and by i.r. spectroscopy in CHCl3 and in the solid state. In this way the relative helix-inducing potential of the two chiral alpha-methyl-alpha-amino acids (S)-Iva and (S)-alpha-MeSer could be established in comparison to the strong helix-former Aib. The results show that (S)-Iva exerts a comparable helix-inducing effect as Aib, making this amino acid a valuable complementary tool for the stabilization or induction of helices. No significant helix-promoting effect was observed for (S)-alpha-MeSer in polar solvents; however, the i.r.-spectroscopic data in CHCl3 and in the solid state point to a helical conformation under these conditions. Possible reasons for the different behaviour of (S)-Iva and (S)-alpha-MeSer are briefly discussed.

Aminoisobutyric Acids↗
PubMed1988

[Mechanical properties of a new vena cava filter].

The construction and the mechanical properties of a percutaneous, transvenous implantable thrombus filter on the pulmonary embolism prophylaxis is introduced. The pressure loss by this filter amounted to nearly 1/60 in comparison with the Mobin-Uddin umbrella filter. The effect of partial occlusions by thrombus is estimated theoretically by means of technical models. The anchoring of the fresh implanted filter is guaranteed in case of embolisation with covering up to 85% of the open surface. A much faster anchoring is to be expected by reaction of the tissue after few days. It also resists in the most unfavourable case imaginable.

Blood Vessel Prosthesis↗
PubMed1987

[Transcutaneous and intracutaneous pO2 measurements in the assessment of peripheral arterial occlusive diseases].

The purpose of the study was to compare the results of intra- and transcutaneous pO2-measurements of patients suffering from an arterial occlusive disease of the lower extremities (Fontaine I-IV) with that of 20 healthy volunteers. The measurements were performed by one transcutaneous and two intracutaneous pO2-electrodes on the dorsum of the foot. As reference we used the ratio pf/pft of the venous occlusion plethysmography of the calf. Already at rest the transcutaneous pO2 allows a significant separation of healthy persons and patients of Fontaine II. After a 3-minute ischemic period the greatly changed time parameters 'delay-time', 'half-time of the pO2 increase' as well as the 'pO2 recovery time' permit a significant separation of Fontaine III from healthy persons and Fontaine II. The findings show that both methods complete one another. The value of a local pO2 measurement for an individual therapy control is emphasized.

Arterial Occlusive Diseases↗
PubMed1986

[Results of ultra-high streptokinase (Awelysin) doses in patients with thrombophlebitis].

The results of 6-hour fibrinolysis with ultra-high streptokinase doses in 30 patients with peripheral venous thrombosis were presented. In 33.3% of the patients complete, and in 40% partial repatency was attained, while no repatency occurred in 20%. Deterioration was observed in two patients. The most beneficial effects were seen in postoperative and posttraumatic thrombosis. Bleeding complications did not occur. In one female patient treatment was discontinued due to bronchospasm.

Adult↗
PubMed1985

[Thrombolytic treatment of peripheral arterial circulatory disorders with streptokinase].

The purpose of these investigations is to refer to the possibility of the reconstructive treatment of arterial obstructions by means of streptokinase. New application methods improved the chances of success of fibrinolysis. They run about 50%. The local application of smaller doses of streptokinase confines the contraindications to a certain extent. Obstruction in the pelvic area which are not older than three months and such ones in the femoropopliteal part up to 6 weeks are to be regarded as indication to the fibrinolysis. In the care of patients with arterial obstructive diseases importance should, therefore, be attached to the fact that thrombotic shifts should be recognized in time an the possibility of a fibrinolytic therapy is tested within the periods mentioned.

Aged↗
PubMed1985

Effect of irradiation on immobilized enzymes compared with that on enzymes in solution.

Glucose oxidase and catalase were immobilized by attaching them to nylon fibers that had been treated with triethyloxonium-tetrafluoroborate, diaminohexane and glutardialdehyde according to Morris, Campbell and Hornby (1975). This method assures that the enzymes are bound to a side chain of the polyamide structure. Enzyme activity (as measured by the O2-uptake and by microcalorimetry) was found to be unchanged after 2 years. The apparent Km-constants of the immobilized enzymes with glucose were the same as those for enzymes in solution. GOD and catalase immobilized in poly(acrylamide) gel had the same Km-value. Despite the high stability during storage, the radiation induced inactivation of enzymes immobilized on gel or chromosorb, an inorganic carrier, was of the same order of magnitude as that of the dissolved enzymes. The enzymes bound to nylon fibers showed a higher radiation sensitivity. This might have been caused by an additional attack on the binding site of the carrier.

Catalase↗
PubMed1983

[Rheologic problems of microcirculation and consequences of drug therapy for sudden deafness].

Microcirculation depends on the undisturbed functioning of the vessel walls as well as of the blood cells and plasma. Flow troubles are always highly complex. Viscosity of blood and plasma is of particular clinical interest, and so are the flexibility of red blood cells including the haemoconcentration and the physiology of coagulation. The authors concentrated on the "local hyperviscosity syndrome", which is one of the primary problems in disturbances of microcirculation, as the basis for their treatment of sudden deafness by fibrinolysis with streptokinase.

Blood Viscosity↗
PubMedDate not supplied

[Early complications after acute cerebrovascular insufficiency].

In the present paper the courses of the disease of 117 patients who due to an acute cerebrovascular insufficiency were admitted to the angiological department of a Dresden county hospital in the period from January 1989 to June 1990. Early complications which were frequently observed were urinary tract infections, pneumonias and recidivations of insult. On the basis of the results of examination can be confirmed that the prognosis is decisively determined by the ability of mobilisation during the first days.

Adult↗