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Biomedical subjects

E Arie

Publications and source records attributed to E Arie.

14 recordsLinked to original sources

Benchmarking: the five year outcome of rheumatoid arthritis assessed using a pain score, the Health Assessment Questionnaire, and the Short Form-36 (SF-36) in a community and a clinic based sample.

BACKGROUND: Treatment, and therefore outcome, of rheumatoid arthritis (RA) will improve in the next few years. However, improvement in outcome can only be judged against the probability of certain outcomes with current conventional treatment. AIM: To document the five year outcome of RA in the late 1990s. SETTING: Norfolk Arthritis Register (NOAR). DESIGN: Longitudinal observational cohort study. METHODS: 318 patients with recent onset inflammatory polyarthritis recruited by NOAR in 1990-91 completed five years of follow up. Four groups were assessed: the whole cohort, all those referred to hospital, those who satisfied criteria for RA at baseline, and those referred to hospital who satisfied criteria for RA at baseline. Outcome was assessed with a visual analogue scale for pain, the Health Assessment Questionnaire (HAQ), and the Short Form-36 (SF-36). RESULTS: Of the RA hospital attenders, 50% had a visual analogue scale pain score of 5 cm or less and an HAQ score of 1.125 or less. SF-36 scores were reduced in all domains. Results are presented as cumulative percentages. CONCLUSIONS: These results can be used for comparison and to set targets for improvement.

Adult↗

Crystal-associated rheumatic disease. Current management considerations.

Safe, effective treatment is available for acute crystal-associated arthropathy. It is time for some older remedies, phenylbutazone and perhaps colchicine, to give way to more modern regimens of combined NSAID therapy and intra-articular steroid injection. Hypouricaemic agents have revolutionised the management of gout but are not without their dangers, and there is a need for re-emphasis on the value of dietary measures and control of alcohol and diuretic use. At present only symptomatic management is available for chronic pyrophosphate- and hydroxyapatite-associated disease.

Anti-Inflammatory Agents, Non-Steroidal↗

Seat-belts again.

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Arthritis, Rheumatoid↗

[Traumatic tricuspid insufficiency. Apropos of a case treated by conservative surgery].

Traumatic tricuspid insufficiency is a rare condition which raises the problem of when and how should its surgical correction be performed. Its diagnosis has been considerably facilitated by echocardiography. We report a case of traumatic tricuspid insufficiency with extensive lesions of the tricuspid valve system, which was diagnosed after a 15-year period without functional signs. Echocardiography and Doppler ultrasounds provided very accurate information on the lesions. Optimal correction was obtained by conservative surgery. The excellent results observed at short and medium term suggest that surgical indications should be extended.

Accidents, Traffic↗

Car safety belts: a study of two models adapted for people with arthritis.

People with arthritis find car seat belts difficult to use. Sixteen arthritic patients and 19 healthy volunteers completed a comparative study of one standard inertia-reel belt and two adapted inertia-reel belts with reduced retraction forces. Those with arthritis were strong enough to use the standard belt but both adapted belts had features making them easier to use.

Adult↗

Femoral head shape in Perthes' disease. Is the contralateral hip abnormal?

Femoral head shape has been assessed in 47 children with unilateral Perthes' disease and 41 control children. Measurements were taken from radiographs and arthrographs by a computerized method. In controls the femoral head was round, particularly in lateral outline, and characteristically asymmetric in anteroposterior views at all ages studied. In children with Perthes' disease the bony femoral head was less round than in controls and flattened anteriorly. Mediolateral symmetry differed from that of controls, reflecting lateral flattening of the cross section of the femoral epiphysis. Age-related changes correlated with disease duration but not with treatment. The "unaffected" hip showed some evidence of anterior and lateral flattening from the time of diagnosis of disease in the other hip. No subject developed bilateral disease during the follow-up period. This early involvement of the "unaffected" hip could indicate a constitutional abnormality. The cartilaginous femoral head was rounder than the underlying bony epiphysis, particularly in anteroposterior views. The cartilage of the hip with Perthes' disease was less round than that on the "unaffected" side. There was no evidence of anterior or lateral flattening of either cartilaginous femoral head.

Adolescent↗