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Biomedical subjects

E Auerbach

Publications and source records attributed to E Auerbach.

At least 19 recordsLinked to original sources

Changes in sensitivity of the dark-adapted eye during concurrent light adaptation of the other eye.

Thresholds for detection of light by a dark-adapted test eye were measured while the other, non-test eye was either similarly dark adapted or while it was exposed to an intense red adapting field. An interocular effect that depends on the retinal location of the test was found: compared to the threshold during binocular dark adaptation, sensitivity decreased during contralateral light adaptation when the test was presented to the foveola and up to 4 deg above it; but sensitivity increased when the test was between 7 and 12 deg, showing a reversal at 5 deg.

Adaptation, Ocular↗

Interocular sensitization to a rod-detected test.

Intense red light adaptation of one eye lowers the dark adapted ("absolute") threshold of a 661 nm, extrafoveal, 1.02 deg test flash in the other eye, by about 0.15 log units, for 10-15 min. This effect ("interocular sensitization") also occurs with an extrafoveal 491 nm test, but does not occur if the 661 nm test is foveal, or is made small and brief. Blue or green light adaptations, matched either photopically or scotopically to the red, do not produce interocular sensitization. Thus the conditions producing the effect include intense red light adaptation of one eye, and scotopically mediated detection in the other.

Adaptation, Ocular↗

Interocular transfer and dark adaptation to long-wave test lights.

Extrafoveal thresholds for 660 nm test flashes were measured for the two eyes separately following 30 min of dark adaptation. Then, the right eye was exposed to red light while the left eye was covered. Thresholds in the adapted right eye recovered to a plateau raised about 0.3 log units above the level measured in the dark. In contrast, thresholds in the nonlight-adapted left eye dropped by about 0.3 log units. These effects persist for about 15 min. They may be accounted for in terms of a hypothetical interocular inhibitory mechanism. Results of changing the intensity, duration and wavelength of the light adaptation upon this effect are described.

Adult↗

Visual defects in the uninjured eye of patients with unilateral eye injury.

We have examined the electroretinographic responses, the psychophysically determined course of dark adaptation and/or the scotopic and photopic (static) perimetric profile of the uninjured eyes of 11 patients with unilateral intraocular foreign bodies. Most of the patients showed subnormal ERG amplitudes over a range of light intensities, and subnormal light sensitivity in isolated retinal areas. The data suggest that eyes not directly injured by a unilateral traumatic ocular episode may show visual defects.

Adolescent↗

The relationship between visual sensitivity and rhodopsin density in retinitis pigmentosa.

Rhodopsin density and absolute threshold were determined in 11 patients with retinitis pigmentosa (RP) and nine normal subjects. In eight patients with familial histories suggesting recessive inheritance, the retinal areas studied showed marked decrease in sensitivity which was related to rhodopsin loss, probably via a log-linear relationship. The other three patients showed absolute thresholds that were linearly related to rhodopsin density, suggesting that sensitivity loss was determined by the decrease in quantal absorption resulting from rhodopsin loss. The results indicate that RP patients can be classified into two categories according to the effects of rhodopsin loss on rod sensitivity. These categories may correspond to different genetic groups. Furthermore, this differentiation may, in fact, reflect different underlying disease mechanisms.

Adolescent↗