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Biomedical subjects

E Azria

Publications and source records attributed to E Azria.

3 recordsLinked to original sources

[Magnesium sulfate in obstetrics: current data].

OBJECTIVE: To review the available evidence regarding history, pharmacology, physiology, maternal/fetal side effects, and efficacy of magnesium sulfate in pregnant women. DATA SOURCES: The literature in Medline was searched from 1966 through April 2003 using the terms "magnesium sulfate," "tocolytic," "preeclampsia," "eclampsia," and "pregnancy." Reviews of bibliographies of retrieved articles provided additional references. RESULTS: Magnesium sulfate (MgSO4) has long been used for prophylaxis of preterm delivery (tocolytic affect) and eclampsia prophylaxis (neuroprotective effect). Randomized controlled trials and systematic reviews have demonstrated the efficacy of magnesium sulfate in preventing eclampsia in patients with preeclampsia or in patients with eclampsia. Whether magnesium sulfate should be administered to patients with severe preeclampsia or to mild preeclampsia is discussed in the manuscript. Inversely, it appears that magnesium sulfate is ineffective in delaying birth or preventing preterm birth when it is used as a tocolytic. Furthermore, there is evidence that high cumulative doses of magnesium sulfate may be associated with increased infant mortality. CONCLUSION: The evidence to date confirms the efficacy of magnesium sulfate therapy for women with eclampsia and preeclampsia. However, magnesium sulfate should not be used in order to treat preterm labor.

Adult↗

[Demons-Meigs syndrome: apropos of 1 case].

A 33-year-old patient presented with ascites and a right abdominal mass. Ultrasound and scannography showed it was probably a solid ovarian tumor measuring 175 mm x 115 mm. Serum Ca 125 was 752 UI/mL and ACE was normal. Surgical exploration revealed 3.2 liters ascites without any suspect peritoneal implant and a bulky ovarian fibrothecoma. The patient recovered quickly and serum Ca 125 was 43 UI/mL one month post-operatively. In this case report of Meigs' syndrome serum CA 125 level was particularly high. Preoperative diagnostic difficulties are discussed.

Adult↗

[The rheopneumography (author's transl)].

The rheograph electrodes, placed in three symetrical leads on the axilla lines, permit recordings to be made of respiratory curves and, during respiratory apnea, of arterial pulmonary curves. The curves were recorded on 296 subjects who were either normal or attacked by lung or pleura diseases. In pathological cases, the respiratory enlargement can be validly reduced; an arterial pulmonary curve can be flattened and show abnormalities that attest to arterial compression (more particularly in cases of lung cancer or pleurisy), to the superposition of a cardiac or systemic arterial curve. An arterial curve can be replaced by a cardiac curve in cases of back-flow or attraction by the heart, an absence of parenchyma between the heart and the paries of the thorax. Information given by this method can be compared but not super imposed with those given by isotopic scanning.

Adolescent↗