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E B Garber

Publications and source records attributed to E B Garber.

4 recordsLinked to original sources

Release of inorganic phosphate from irradiated yeast: radiation biodosimetry and evaluation of radioprotective compounds.

When cells of bakers' yeast, Saccharomyces cerevisiae, were irradiated with ionizing radiation, inorganic phosphate, ninhydrin-reactive material, and substances absorbing at 260 mmu were released into the suspending medium. The amount of inorganic phosphate released depended on the radiation dose and on the temperature and pH during irradiation. The concentration of yeast cells did not affect the phosphate yield per milligram of yeast. It is suggested that the release of phosphate may serve as an index of the total radiation environment (i.e., as a biodosimeter) where radiation inactivation of microrganisms is of primary importance, e.g., in radiation preservation of foods. The somewhat limited range of the yeast biodosimeter (ca. 0.5 to 1.75 Mrad) may be extended by use of other more resistant microorganisms, such as bacterial spores. Compounds which have been reported as protecting microorganisms and mammals against the lethal effect of ionizing radiation also inhibited the radiation-induced release of inorganic phosphate from yeast. This phosphate release system is proposed as the basis for an economical, rapid supplement to screening procedures in the evaluation of radioprotective compounds.

Colorimetry↗

Left atrial size in patients with atrial fibrillation: an echocardiographic study.

Left atrial dimensions were recorded echocardiographically in 50 patients with atrial fibrillation. Fibrillatory wave amplitude (f wave) was measured in lead V1 of standard electrocardiograms for all patients. Left atrial dimensions (LAD), LAD compared to body surface area (LAD/M2) and the ratio of LAD to aortic root diameter (LAD/AR) were calculated. There was no significant correlation between f wave size and LAD (p = 0.6480), between f wave size and LAD/M2 (p = .6721), or between f wave size and LAD/AR (p = .1157), nor was there any association between LAD and the etiology of the heart disease. F wave size did correlate (p = .0073) with the age of the patient, the older the individual, the more likely was he to have fine atrial fibrillation (peak to trough f wave less than 0.5 mm).

Action Potentials↗