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Biomedical subjects

E B Kay

Publications and source records attributed to E B Kay.

At least 19 recordsLinked to original sources
PubMed1989

Early years in artificial valve development.

Various types of prosthetic heart valves developed and tested in the laboratory beginning in 1958 are described. Seven of such valves were implanted clinically in patients with congestive heart failure previously operated on by both the closed and open techniques in 1958 and 1959. The longest survivor was 6 weeks. Evidence is presented demonstrating that putting a film of polyurethane on the Teflon leaflet valve and fixation rings of disc valves reduces thrombosis, thromboembolism, and tissue overgrowth interfering with disc or ball valve function.

Aortic Valve↗
PubMed1986

Physiological adaptability: the secret of success of the internal mammary artery grafts.

Angiographic studies in 3 patients illustrate the physiological adaptability of internal mammary artery (IMA) grafts. Intact vascular smooth muscle permits the IMA grafts to retain a flexible caliber and a blood flow dictated by myocardial demands in the distribution of the grafted coronary artery. This physiological nature may be one of the reasons for their continued patency regardless of whether they are grafted to large or small coronary arteries. Further, this adaptable behavior permits use of the IMA even if its distal lumen is smaller than that of the recipient coronary artery, provided the anastomosis can be safely performed and the demand for flow is present.

Coronary Disease↗
PubMed1985

Internal mammary retractor.

A new retractor for dissection of internal mammary arteries is described. We have found that the instrument can easily be applied to the chest wall and gives excellent exposure for dissection of the graft from origin to bifurcation.

Coronary Artery Bypass↗
PubMed1975

Coronary venous retroperfusion for myocardial revascularization.

Although the use of retrograde arteriovenous bypass perfusion may seem appealing in those patients with diffuse occlusive coronary artery disease in whom arterial bypasses are not possible, the likelihood of success seems small. Experimental evidence indicates that such retroperfusion in opposition to antegrade perfusion causes the myocardium to become hemorrhagic. Further experimental evidence indicates that this damaging effect on the myocardium may be prevented by a second bypass which vents the arterial side to a low-pressure system.

Animals↗