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E B Rodzaevskaia

Publications and source records attributed to E B Rodzaevskaia.

2 recordsLinked to original sources

[Morphological impairment of oogenesis in experimental iodine-dependent thyroid transformation].

Histophysiology of white rats' ovaries was studied in iodine-deficient and iodine-enriched diets; in such diets kept in pregnancy or postnatal period. The iodine-deficient diet leads to low histofunctional thyroid activity, formation of cysts in the ovaries, slow folliculogenesis, hypotrophy of yellow body tissue, overgrowth of the connective tissue, thickening of the theca of the cavernous follicles, hardening of the vessels of the cortical and core substances. The fertility fell by 18%. In long-term intake of iodine-rich diet and in pregnancy essential intensification of histofunctional activity of the thyroid gland was noticed and in the ovaries there was a distinct hypertrophy of the yellow bodies, hyperplasia of lutein cells, endomitosis. Postnatal structural changes of the gonads were registered as well as micro- and macrocystic degeneration of yellow body tissue, atretic and cavernous follicles, dystrophic transformation of interstitial tissue.

Animals↗

[Age-dependent thymus involution in experimental iodine deficiency].

The experiment on white Wistar rats provided morphometric and morphofunctional evidence on correlations between the thyroid and thymus in health and thyroid transformation in iodine deficiency. In chronic iodine deficiency the rate and volume of thymic physiological involution increase. Total shrinkage of the parenchyma of cortical and core substances of thymic lobules from juvenile animals reaches 25% in the experimental group vs 11% in the reference group. The absolute mass of the organ was stable due to increased volume of connective tissue of the interlobular septa and intralobular perivascular spaces. Iodine-dependent thyroid transformation brings about profound changes in correlations between tissue components and cellular subpopulations of the thymic lobule indicating disturbed mechanisms of immunological regulation in iodine deficiency.

Aging↗