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Biomedical subjects

E Baden

Publications and source records attributed to E Baden.

At least 37 records · Page 2Linked to original sources
PubMed1983

The effect of chronic beta-aminoproprionitrile intoxication on the periodontium of the rat. A light microscopic and histochemical study with review of the literature.

This histologic study of the periodontium of male white rats with chronic lathyrism demonstrates the appearance, progression, and persistence of certain pathologic changes caused by disordered collagen synthesis and maturation. Typical lesions were seen after 6 weeks. These include increased vascularity, especially in the periapical region, hyalinization and calcification of the transseptal fibers, alveolar bone and cementum resorption, interruption of the periodontal fibers with formation of typical hyaline zones surrounded by palisades of atypical fibroblasts, known as "lathyritic bodies," and an increase in mast cells.

Alveolar Process↗
PubMed1982

The peripheral ameloblastoma of the gingiva. Case report and literature review.

A new case of the rare peripheral ameloblastoma of the gingiva is presented. Also the clinical and histomorphologic characteristics of the lesion were analyzed and studied in all previously documented cases. This tumor, and the basal cell carcinoma of the gingiva, probably represent the same lesion. It meets the same microscopic criteria as the intraosseous ameloblastoma, but its behavioral and clinical characteristics are completely different. The peripheral ameloblastoma usually occurs in the gingiva, is noninvasive, and local excision is usually curative. Recurrence of the neoplasm is uncommon, except when it is incompletely excised. The histogenesis and varied cellular pattern of the peripheral ameloblastoma and several other related odontogenic lesions of the gingiva illustrate the proliferative and differentiation potential of the basal cell layer of gingival epithelium.

Ameloblastoma↗
PubMed1982

The effect of beta-aminoproprionitrile on the lingual artery and aorta of the rat: a light microscopic study.

The effects of chronic toxicity of beta-aminoproprionitrile (BAPN) on the lingual artery and aorta of the rat were compared. Thirty-two three week old weanling male white Wistar rats were given 1 g/kg/day (for five days weekly) of a 40% saturated solution of BAPN fumarate by intragastric tube. The animals were divided into four groups of eight animals each and sacrificed after one, three, six and nine weeks respectively. For each group, four controls were used. Cross-sections of the lingual artery and aorta stained with hematoxylin-erythrosin-safranin, alcian blue, Masson's trichrome and Verhoeff's iron hematoxylin were studied. BAPN had no effect on the lingual artery. Early changes were seen in the aorta at six weeks. Characteristic lesions were found at nine weeks involving the elastic tissue, myocytes and ground substance. The elastic lamellae were thinner, lost their normal orientation, and became swollen and finally fragmented. The myocytes of the media changed orientation and migrated into the intima. The proteoglycans increased and fibrosis supervened at the end stage. Failure to induce lesions in the lingual artery may be explained by early structural maturation and a low metabolic turnover rate in muscular arteries, decreased exposure to or greater protection from mechanical stress.

Aminopropionitrile↗
PubMed1977

Liposarcoma of the oropharyngeal region. Review of the literature and report of two cases.

Liposarcomas of the oropharyngeal regions are exceedingly rare. Their silent, slow growth, submucosal or deep location, circumscription, and firm but resilient texture often suggest a diagnosis of a cyst or benign soft-tissue neoplasm. Two cases of well-differentiated myxoid liposarcoma are presented. The literature of over half a century was reviewed, and all documented cases were critically analyzed. The clinical data correlated with the histopathology and biologic behavior of the tumors indicated that two thirds of all liposarcomas of the head and neck are of the myxoid type. The well-differentiated myxoid liposarcoma was the most common one and has an over-all favorable prognosis. Lipomas of the oropharyngeal regions are relatively common and small, generally not exceeding 2.5 cm. in greatest diamter. A lobulated firm tumor of fast tissue significantly exceeding this size should be strongly suspected of being a liposarcoma.

Adult↗
PubMed1976

Intraoral papillary cystadenoma lymphomatosum.

The literature related to intraoral papillary cystadenoma lymphomatosum is critically reviewed and the reported cases analyzed to determine the average age, sex, and race of patients, and the site distribution of this curious lesion. Two new cases are reported. The histogenesis and differential diagnosis from cystadenocarcinoma are briefly discussed.

Adenolymphoma↗
PubMed1975

Successful treatment of mucocutaneous mucormycosis after dental extractions in a patient with uncontrolled diabetes.

A successfully treated case of mucocutaneous mucormycosis, after dental extractions in a patient with uncontrolled diabetes, has been reported. The pathophysiology of diabetes mellitus that contributes to the development of opportunistic fungal infections and gangrenous ulcerations, in a setting of decreased host resistance, has been discussed with reference to differential diagnosis and management. The consequences of operating on a patient with uncontrolled diabetes are evident.

Adult↗
PubMedDate not supplied

Prevention of cancer of the oral cavity and pharynx.

Multiple environmental factors and a multistage pathogenic mechanism appear to be involved in oropharyngeal carcinogenesis. Tobacco and alcohol are the most important risk factors, but other agents may also contribute to malignant transformation. Individual susceptibility to environmental carcinogens, although significant, is still incompletely understood. Based on our present-day knowledge of risk factors, prevention should be possible in about two thirds of all oropharyngeal cancers. It cannot be achieved, however, without both public and professional education. A rational approach to prevention of oropharyngeal cancer should start in school before habits are formed, continued throughout adolescence, and reinforced in adults. Reduction or elimination of risk factors is of prime importance. For those who cannot quit tobacco, a reduction of tar content in cigarettes, cigars, pipes, and chewing tobacco, and elimination of nitrosamines, especially from smokeless tobacco, might also help to reduce risks. Control of chronic alcoholism is more difficult, but diet supplementation, especially with proteins, vitamins, and trace metals, would decrease the promoter effect of alcohol. Control of occupational risks is of less significance. The clinician must have a state-of-the-art understanding of all known risk factors for the prevention, early detection, and control of oropharyngeal cancer. The history should review in detail exposure to tobacco, alcohol, actinic radiation, and other agents. Age of first exposure or onset of habit; duration (years); quantity of tobacco smoked, chewed, or snuffed; and its relationship with the anatomic site at risk should all be precisely recorded. Exposure to alcohol or any other risk factor should be evaluated in the same way. This review has emphasized the relationship between the various risk factors and the site prevalence of malignant lesions. Habits, customs, and cultures, as well as anatomic physiologic factors, all have a bearing on the actual target sites at which the carcinogen(s) and promotor(s) are brought in contact with the oral mucosa. Habits and customs vary widely, both geographically and among individuals. Dentists and physicians should be aware of these individual factors as they examine their patients.

Alcoholism↗