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Biomedical subjects

E Baraggino

Publications and source records attributed to E Baraggino.

At least 19 recordsLinked to original sources

[Villoglandular adenocarcinoma of the cervix uteri. A case report and analysis of the literature].

The authors described a case of villoglandular adenocarcinoma of the uterine cervix treated with radical hysterectomy (Piver type 2) and pelvic lymphadenectomy. The cytohistologic and clinical aspects of this rare neoplasia are debated also considering the literature data where, until 1996, 41 cases of villoglandular adenocarcinoma of the uterine cervix were reported (10 cases at Stage 0 and 31 cases at Stage IB), all with favorable prognosis.

Adenocarcinoma↗

Study of the partners of women with human papillomavirus infection.

BACKGROUND: Genital human papillomavirus (HPV) infection is one of the most common sexually transmitted diseases, and it has been identified as a significant risk factor for the development of dysplasia and cancer of the uterine cervix. The possible influence of male HPV lesions on female cervix oncogenesis has not been elucidated so far. In the present study we evaluate the male partners of women with clinical or subclinical HPV infection with particular interest in the clinical features of this infection in both partners. METHODS: We examined 81 male partners of women affected with human papillomavirus infections. Condylomata acuminata were searched for by visual inspection. Subclinical lesions were searched by 5 power optical magnification lens after application of 5% acetic acid. RESULTS: In men we observed the following percentage of infection: 67% of the partners of women affected with condylomata acuminata, 46% of the partners of women affected with subclinical lesions (acetic acid positive), and 40% of the partners of women with association of HPV and cervical intraepithelial neoplasia. CONCLUSIONS: Our data stress that very often the partners of women with HPV subclinical infection, especially when associated with CIN, do not present lesions, and consequently primary prevention may be very difficult.

Adolescent↗

[Preliminary clinical study of the use of itraconazole in the treatment of vulvovaginal candidiasis].

Thirty women (28 of childbearing age and 2 in the menopause), affected by acute Candida albicans vulvovaginitis were treated orally with a new antimycotic triazole derivative, itraconazole. Twenty patients were administered with 200 mg/die of itraconazole for three days. In tests carried out 7 and 30 days after the end of therapy the following results were observed. Negative cultures in 95% of patients and in 75% of patients; absence of leukorrhea in 60% of patients and in 65% of patients; disappearance of pruritus in 95% of patients and in 80% of patients. Ten patients were administered with an acute dose of itraconazole (400 mg). In the same tests, carried out 7 and 30 days after the end of therapy reported above the results were as follow. Negative culture in 80% and 60% of patients; absence of leukorrhea in 50% and 60% of patients; absence of pruritus in 70% and 50% of patients. In the first group of patients one case of slight nausea was reported whilst in the second group there were two cases of nausea, one of gastralgia and one of urticaria. No systemic side-effect was seen.

Adult↗

[Therapeutic proposals in vulvar dystrophy and burning vulva].

The paper reports the results of 80 cases of vulvar dystrophy and 11 cases of burning vulva. The Authors put forward a protocol for therapy which also aims to provide the basis for a comparative study of this pathology about which little is known from a clinical and research point of view.

Administration, Topical↗

Cancer of the endometrium in the province of Trieste: epidemiological considerations.

The Authors examined the epidemiological behaviour of endometrial carcinoma in the Province of Trieste from 1969 to 1980. In this period a European standard incidence of 14.33(0)/0000 was recorded. The most affected age group is 60 to 69, and the average age is 64 years. A clear increasing trend of this kind of neoplasia was recorded. This increase mainly occurs in younger age groups than those which presently are most affected.

Adult↗

Invasive cancer of the uterine cervix in the Province of Trieste: epidemiological considerations.

The epidemiological behaviour of the invasive cancer of the uterine cervix in the Province of Trieste is analysed. During this study period, 488 cases of this neoplasia were diagnosed with an incidence rate standardized for the European population of 20.25 degrees/0000. This value is within the average ones recorded in other geographic regions. The age group which is most affected is that from 60 to 64 years. By analyzing the overall incidence rate of the first two years if compared with the last two years of our study period, a 29% decrease is recorded, with an annual average decrease of 2.6%. This value is one of the highest reported in the literature. This decrease is recorded in the age groups over 40, while no decrease is recorded in women under age 40.

Adult↗

Diagnostic cytology in breast cancer screening.

In the period 1977-1978, 245 solid or cystic breast tumors and 134 nipple secretions were evaluated cytologically at the Trieste Cancer Institute. The results are discussed in the light of literature reports, and the high incidence of unsatisfactory smears observed in the group of malignant lesions (14,7%) is attributed to incorrect technique in specimen collection. The incidence of false positives and false negatives was 0,2% and 2,9%, respectively. The data reported are insufficient for significant statistical conclusion, but nevertheless confirm further the diagnostic importance of breast cytology whose routine practice in patient study protocols for breast cancer is highly recommended.

Adenocarcinoma, Mucinous↗

Endometrial cytology during menstrual cycle, menopause and progestinic treatment.

The AA. examined 72 cytological smears of the human normal endometrium. Twenty-three were taken during the proliferative phase, 17 during the secretory phase, 21 during menopause and 11 during estro-progestinic treatment. The study pointed out that the endometrial smear, which has been employed up to now almost exclusively in the cyto-oncological field, is also quite suitable for a dynamic cyto-functional evaluation of ovarian function, because of the series of interpretative elements, easily and readily identifiable at the microscope, which it furnishes.

Endometrium↗