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Biomedical subjects

E Barbu

Publications and source records attributed to E Barbu.

At least 19 recordsLinked to original sources
PubMed1978

[Variation in delayed hypersensitivity to methylated bovine serum albumin as as function of the dose and time of administration of cyclophosphamide].

The injection of Cy before immunization provokes an intensification of delayed-type hypersensitivity (DTH) to methylated bovine serum albumin (M-BSA) and a diminution of about 90% of the cell number in various lymphoid tissues. The relationship between these observations, the time of administration, the dose of injected Cy and the intensity of DTH reactions, allows us to formulate hypotheses concerning the physiological modulation of DTH.

Animals↗
PubMed1977

[The migration, localization, and lysis of transferred lymphocytes in the mouse].

10 days after the injection of lymphocytes labeled with 51Cr, in the footpads of syngenic mice, 70 p. cent of the label is still present in the footpads. The 51Cr that comes out of the lymphocytes is eliminated from the footpads in less than 24 hrs. In this way it is possible to study the cytolysis of allogenic lymphocytes in vivo.

Animals↗
PubMed1976

[The transfer of delayed hypersensitivity in mice].

Independently of histocompatibility between donors and recipients, delayed type hypersensitivity can be transferred with splenic cells from sensitized animals, inoculated locally in the foot pad. Cyclophosphamide given to recipients 48 hrs. before the cells increases significantly the intensity of the transferred delayed type hypersensitivity.

Animals↗
PubMed1975

[Modulation of delayed hypersensitivity by antibodies].

Immunsera against methylated bovine serum albumin (M-BSA) inoculated into mice before sensitization to M-BSA produced a diminution of the delayed hypersensitivity to M-BSA. Immunsera to some modified or native BSA did not produce the same effect which appears to be highly specific.

Animals↗
PubMed1975

Lymphographic aspects of the barrier function of lymph nodes in Hodgkin's disease.

The persistence of Lipiodol in various lymph node groups was followed up by systematic lymphographic control. Assuming a certain relationship between the barrier function of the lymph nodes and the persistence of their image on the film the authors have tried to find out whether the duration of Lipiodol persistence may be a test for the estimation of prognosis in Hodgkin's disease. The observation of such cases has shown that Lipiodol is retained for a longer period in the external iliac and lombo-aortic lymph nodes as well as in the pathologic ones, except those with lymphocyte depletion, whereas it is very rapidly eliminated from the inguinal nodes. These findings seem to prove that Hodgkin's disease is more severe in patients in whom the barrier function of the lymph nodes is defective i.e. unable to retain the foreign substances introduced in the organism. These conclusions should be further verified by comparison with other clinical and biologic factors.

Hodgkin Disease↗