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Biomedical subjects

E Barzilay

Publications and source records attributed to E Barzilay.

32 records · Page 2Linked to original sources
PubMed1983

Synchronized intermittent mandatory insufflation of the endotracheal tube cuff.

Continuous inflation of endotracheal tube cuffs causes tracheal injury in up to 11% of intubated patients. To avoid this complication and its consequences of tracheal and laryngeal stenosis and tracheoesophageal fistula, we designed a simple device which enables intermittent inflation of the cuff during inspiratory periods of mechanical ventilation. This was achieved by connecting the inlet of the cuff of the pressure regulating tubing of the expiratory valve of a Bennett respirator. We have used the device in 25 patients with prolonged intubation. There was no air leak around the tube, no aspiration of gastric content, and no late complications as shown by direct laryngoscopy at 1 week, 1 month, and 3 months after extubation, and by X-ray of the upper airway.

Adolescent↗
PubMed1983

The use of conventional ventilators for high frequency positive pressure ventilation.

Ten randomly selected patients were ventilated for defined periods with 2 ventilatory modes: (a) high frequency positive pressure ventilation (HFPPV) (frequency 66-70 min; tidal volume 1-3 ml/kg body weight), (b) conventional IPPV (frequency 16/min; tidal volume (VT) 10-15 ml/kg). This was done successfully using conventional ventilators, and keeping other variables (FIO2, PEEP) constant. Various ventilatory and hemodynamic variables were measured and compared during both modes of ventilation. The most prominent finding was a considerable reduction of cardiac output (CO) and stroke volume (SV) during intermittent positive pressure ventilation (IPPV) compared with HFPPV. Peak tracheal pressure was significantly lower during HFPPV. An increase in mean systemic arterial pressure and in oxygen transport was observed during HFPPV, whereas transpulmonary shunt and pulmonary vascular resistance (PVR) decreased during HFPPV. These findings are in accordance with previously reported advantages of HFPPV, and might be of importance in the treatment of patients with bronchopleural fistula, adult respiratory distress syndrome (ARDS), left ventricular failure and other conditions in which conventional positive pressure ventilation (PPV) fails.

Adult↗
PubMed1982

Treatment of cardiogenic shock with nitroglycerin infusion and high-frequency positive pressure ventilation.

A patient with chronic obstructive lung disease developed severe cardiopulmonary failure following acute myocardial infarction. High frequency positive pressure ventilation achieved good ventilation. The hemodynamic status was markedly improved when, in addition to dopamine, nitroglycerin was infused into the pulmonary artery. Within 24 h the cardiac index increased, and mean pulmonary artery pressure and pulmonary vascular resistance decreased. Pulmonary wedge pressure decreased more slowly than the pulmonary artery pressure and to a lesser extent. This critically ill patient responded very well to the treatment and was discharged in good health after 18 days in the General Intensive Care Unit. Intravenous nitroglycerin is a promising drug for the treatment of severe cardiopulmonary emergencies and should be tried in patients with chronic lung disease and acute cardiac or respiratory failure.

Blood Gas Analysis↗
PubMed1982

Mechanical ventilation in fiberoptic-bronchoscopy: comparison between high frequency positive pressure ventilation and normal frequency positive pressure ventilation.

High frequency positive pressure ventilation (HFPPV) was compared with normal frequency positive pressure ventilation (NFPPV) during diagnostic fiberoptic-bronchoscopy. HFPPV was achieved by a simple modification of the Minivent, and gave satisfactory alveolar ventilation and oxygenation. In all 11 patients and over periods of at least 40 min, HFPPV gave normal PaCO2 and high levels of PAO2. Arterial blood pressures were higher and the airway pressures were lower than during NFPPV.

Adult↗
PubMed1981

Adult respiratory distress syndrome treated with high-frequency positive pressure ventilation.

Adult respiratory distress syndrome (ARDS) is a severe disease that carries a poor prognosis (50 to 60% mortality). Although modern ventilatory techniques, especially positive end-expiratory pressure ventilation, have reduced the mortality rate somewhat, they are still far from serving as the ideal solution to this grave condition. High-frequency positive pressure ventilation (HFPPV) is a relatively new technique that enables effective alveolar ventilation without creating high intrapulmonary pressures. HFPPV using a conventional ventilator, Bennett MA-1B (Suffex, England), was tried in a 22-yr-old man with ARDS due to pyocyanea sepsis, who had failed to respond to conventional ventilation. A dramatic improvement was achieved within 60 min of increasing the ventilatory rate from 12 to 80/min, with a concomitant decrease of tidal volume from 12 to between 2 and 23 ml/kg. HFPPV may be a useful alternative method in the treatment of patients with ARDS.

Adult↗
PubMedDate not supplied

Respiratory function following premedication with droperidol or diazepam.

Respiratory function was measured before and 1 hour after premedication with diazepam (10 mg IM) or droperidol (5 mg IM) in 2 groups of 14 normal patients scheduled for elective surgery. Diazepam had no significant effects on respiratory rate, tidal volume, minute ventilation, dead space, VD/VT %, alveolar ventilation, expired Po2, or Pco2, end-tidal Pco2, arterial Po2 or Pco2, or alveolar-arterial Po2 or Pco2 gradients. Droperidol was associated with statistically significant but modest reductions in tidal volume (-13.3%) and minute ventilation (-8.4%) while other respiratory functions remained unaffected.

Adult↗