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Biomedical subjects

E Beleites

Publications and source records attributed to E Beleites.

26 records · Page 2Linked to original sources
PubMed1986

[Olfactory neuroblastoma. 3 case reports as a contribution to the clinical aspects, morphology and prognosis].

The leading symptom in all patients was a nasal obstruction. At first all three cases of olfactory neuroblastoma were mistaken for polyposis nasi. The tumour can be diagnosed solely by histologic examination. The light microscopic as well as the ultrastructural findings demonstrated the great morphological variability of this carcinoma. In nearly all cases a definite diagnosis is possible if besides the light microscopic picture also clinical data, ultrastructural and, if necessary, immunohistochemical findings are considered. At the time of diagnosis one tumour was Kadish-stage A and two were stage C. Lokal and metastatic tumour extension, recurrence of disease after treatment, patient age and radical tumour resection at initial presentation, are prognostic important criteria. The discriminant function by Homzie and Elkon permits the oncologist to predict the patient's outcome accurately.

Adult↗
PubMed1985

[Scanning electron microscopy study of cell growth on mechanically produced biovitroceramic and carbon glass in vitro and in vivo].

New machinable glass ceramics were tested for the application in middle ear surgery in vitro and in vivo. This ceramic consists of a glass phase and a glimmer phase. Fibroblasts and epitheloid cells seated on the test material attach to it, spread and form a confluent monolayer. From our findings on the behaviour of cell populations in vitro we can conclude that the implanted material is biocompatible. After implantation into the middle ear of rabbits, irritation-free settling was verified by the existence of a thin epithelium layer and a direct connection between bone and implant. Glass carbon did not yield equally satisfactory results.

Animals↗
PubMed1983

[Incidence of regional metastasis in supraglottic carcinoma].

In 348 patients with supraglottic carcinoma 154 (44%) had palpable lymph nodes. Only 26% of the patients treated surgically showed histologically abnormal nodes in the neck. The incidence of regional metastasis increased to 33% including latent lymph node metastasis. There were 4 patients (5%) with positive nodes on histologic examination which had not been detected clinically (N0). In N1- and N2-patients, histologically positive nodes were found in 41% and 29%, respectively. A fixed node (N3) was nearly always a positive node. Postoperative TNM-classification is very important in terms of prognosis of the supraglottic carcinoma. The presence of metastasis in regional lymph nodes decreased the 5-year-survival rate from 64% to 43%. Because of the high frequency of lymphatic metastases of the supraglottic carcinoma, the aim of radical surgery should include the removal of regional metastases and of the potential bilateral avenues of spread. This principle is indicated even though lymph nodes may not be palpable in partial laryngectomy.

Carcinoma↗