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Biomedical subjects

E Bergquist

Publications and source records attributed to E Bergquist.

At least 19 recordsLinked to original sources
PubMed1988

Methodological analysis of an experimental spinal cord compression model in the rat.

A technique for producing graded spinal cord compression injuries in rats is described. A metal plate 2.2 x 5.0 mm in size is applied to the exposed spinal dura and loaded with weights. Neurological function is tested postoperatively on an inclined plane. Reading of the maximal angle of rat performance on this plane was found reproducible on comparison between different observers. Laminectomy per se had a minimal effect on the performance. Compression of 35 g for 5 min caused a pronounced but incomplete injury, with almost total recovery within 14 days and with no difference between animals on artificial respiration and those breathing spontaneously. Animals whose spine was fixed during the compression had a better outcome than those without such fixation.

Animals↗
PubMed1978

Cholera, non-vibrio cholera, and stomach acid.

Fasting and postprandial stomach acid production were low in 16 of 37 Bangalees convalescing from cholera or non-vibrio cholera. Gastric juice of hypochlorhydric patients did not kill cholera vibrios in vitro, whereas that from normochlorhydric patients rapidly killed vibrios in concentrations up to 10(10)/ml. To determine whether hypoacidity resulted from cholera or was a common predisposing factor, basal and betazole-hydrochloride-stimulated acid production were measured before and after cholera in a second group of patients consisting of American volunteers participating in a vaccine development programme. Cholera did not alter the stomach acid secretion of American volunteers, but low precholera basal acid production predispose to severe cholera. The results indicate that hypochlorhydria observed in convalescent Bangalee cholera patients is not caused by cholera, and must therefore have preceded it. Idiopathic tropical hypochlorhydria may be a major factor accounting for the high incidence of diarrhoea due to acid-sensitive pathogens in developing countries.

Achlorhydria↗
PubMed1978

Cannabis, hypochlorhydria, and cholera.

In 90 volunteers participating in a vaccine-development programme consumption of beer more than 3 days a week was linked with high stomach acid output, and smoking of cannabis greater than 2 days a week was linked with low acid output. In 92 volunteers challenged with Vibrio cholerae or enterotoxigenic Escherichia coli, heavy use of cannabis was associated with more voluminous diarrhoea. Cannabis use may be an important factor predisposing to severe diarrhoea.

Achlorhydria↗
PubMed1975

Fibrous septa in the straight dural sinus.

Postmortem exploration of the straight sinus supplemented in some cases by radiography revealed the presence of single or multiple septa or synechiae in the sinus in 44 of 145 cases. A septum should not be mistaken for a thrombus. The septa are of roentgenologic significance because of their ability to alter the appearance of the sinus from one cerebral angiography to another in one and the same patient.

Adult↗