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Biomedical subjects

E Berman

Publications and source records attributed to E Berman.

At least 163 records · Page 9Linked to original sources
PubMed1981

Observations of rat fetuses after irradiation with 2450-MHz (CW) microwaves.

Female Sprague-Dawley (CD) rats were exposed to 2450-MHz (CW) microwave radiation at incident power densities of 0 or 28 mW/cm2 for 100 min daily on the 6th through 15th day of gestation. The whole-body specific absorption rate at 28 mW/cm2 is estimated to be 4.2 W/kg. These exposure conditions raised rats' average colonic temperatures to 40.3 degrees C at the end of irradiation. There were 67 sham-irradiated and 70 microwave-irradiated females. When these groups were compared, no significant differences were found in pregnancy rates; in the numbers of live, dead, or total fetuses; in the incidences of external, visceral, or skeletal anomalies or variations; or in the body weight of live fetuses. It is concluded that these conditions do not have an effect on the gross structure of the fetal rat when applied repetitively during post-implantation pregnancy. It is also strongly suspected that this lack of an effect may hold true at any exposure level less than that which will kill a significant number of the dams by hyperthermia (colonic temperature greater than 40 degrees C).

Animals↗
PubMed1981

Emotional reactions of expectant fathers to their wives' first pregnancy.

A group of 51 expectant fathers, whose wives were in the last three months of their first pregnancy, was compared to a control group of 51 married men without children. On the Anxiety Scale Questionnaire the expectant fathers were significantly higher in overall anxiety (both overt and covert), as well as in tension and apprehensiveness. The Blacky Picture Test indicated stronger Oedipal intensity, sibling rivalry and guilt feelings in the experimental group than in the control group. Clinical interviews with six of the subjects revealed considerable ambivalence, frequently related to re-aroused infantile fantasies, feminine identifications, castration fears and Oedipal themes, as well as attempt to defend against the ambivalent feelings through negation, denial, isolation, repression, intellectualization and reaction formation. While the higher levels of anxiety could be understood as a reaction to a reality stress situation, the Blacky Test results and the interview material point to more specific dynamic factors, and support several psychoanalytic hypothesis about significance of pregnancy for the prospective father. The inner conflict aroused contributes to the intensified anxiety, which is likely to be overdetermined.

Adult↗
PubMed1981

Multiple personality: psychoanalytic perspectives.

Multiple personality, which played a central role in psychiatry and psychology in the era of Janet and Prince, also attracted the interest of Freud and Breuer, and was utilized by Freud as a model for some of his early formulations. Later, with his distancing from Breuer and rivalry with Janet, and with the growing emphasis upon repression at the expense of dissociation. Freud's interest in multiple personality diminished. This change is reflected in the relative neglect of the topic in psychoanalytic literature. It is suggested, however, that psychoanalysis needs and is able to deal with this phenomenon, and several contributions are suggested as potential foundations: Freud's later thought on identification and on splitting; Fairbairn's work on object relations and ego splitting, which may be recast in terms of the representational world; Kernberg's writings on borderline personality organization; and Kohut's formulation of 'the vertical split'. Three recent cases of multiple personality are presented, and an attempt is made to analyse their development and dynamics. Severe deficits in mother-child relationship are evident in all three, and are seen as the primary source of splitting. An intense and unresolved compensatory oedipal involvement, followed by loss, leads to the open appearance of the split. The separate 'personalities' represent complex crystallizations of part object representations which evolve into split self representations. In view of the developmental arrest which can be observed, the therapeutic strategy suggested is not based on confrontation and interpretation of the distortions and denial involved, but rather on developing faulty ego functions and empathically strengthening the fragmented self.

Adolescent↗
PubMed1980

Natural abundance carbon 13 nuclear magnetic resonance spectroscopy of antifreeze glycoproteins.

Natural abundance 13C NMR spectroscopy (at 67.9 MHz) is used to study an aqueous solution of the antifreeze glycoproteins 3 to 6 from the Antarctic cod. Assignments of resonances to specific carbons of the known Ala-Ala-[beta Gal-(1 leads to 3)-alpha-N-acetylgalactosamine]Thr repeating unit are presented. Some of the carbons of the proline residues of glycoprotein 6 are also identified. Spin-lattice relaxation times (at 30 degrees C), linewidths (at 35 degrees C), nuclear Overhauser enhancements (at 35 degrees C), and the temperature dependence of chemical shifts (from 0 degrees to 75 degrees C) all strongly suggest that these antifreeze glycoproteins are predominantly or entirely flexible random coil polymers.

Amino Acids↗
PubMed1980

Tests of mutagenesis and reproduction in male rats exposed to 2,450-MHz (CW) microwaves.

Tests of mutagenesis and reproduction were conducted in male rats which were irradiated by 2,450-MHz, continuous-wave (CW) microwaves, 4 hr/day from day 6 of gestation to 90 days of age at 5 mW/cm2; or 5 hr/day for five days beginning on the 90th day of age at 10 mW/cm2; or 4 hr/day, 5 days/wk for four weeks, beginning on the 90th day of age. During selected weekly periods after treatment, the rats were bred to pairs of untreated, normal female rats that were examined in late pregnancy by means of dominant lethal assay. The reproductive efficiency of these males, as reflected in their breeding, was also examined for changes relating to their microwave experience. No significant evidence of germ-cell mutagenesis was detected when data of microwave-exposed males were compared with those of sham-exposed males, even though there were significant increases in rectal and intra-testicular temperatures at a power density of 28 mW/cm2. Temporary sterility, as indexed by fewer pregnancies, was seen at the highest power density.

Animals↗
PubMed1978

An overview of results of world-wide clinical trials with cefadroxil.

Céfadroxil, a new semisynthetic oral cephalosporin, is absorbed similarly by fasted and non-fasted subjects, produces sustained serum levels and is eliminated at a relatively slow rate. These pharmacokinetic properties permit less frequent and more convenient dosage scheduling than cephalexin and cephradine and consequently greater patient compliance. Cefadroxil was evaluated for safety in 1051 patients and for efficacy in 1030 patients. Overall it achieved a 91.8% rate of clinical success resulting from 881 complete cures and sixty-five clinical cures. Among 363 patients with respiratory tract infections and 471 patients with genito-urinary tract infections, cefadroxil treatment produced 97.5% and 84.5% clinical success, respectively. In the remaining infectious diseases treated, cefadroxil therapy resulted in 99.0% clinical success. Cefadroxil eradicated 87% of 1110 pathogens isolated, among which the most predominant pathogens were Staphylococcus aureus, beta-haemolytic streptococci, Streptococcus pneumoniae, Escherichia coli and Proteus mirabilis. Drug-related side-effects were reported in 7.2% of the patients.

Adolescent↗
PubMed1976

A review of results of clinical trials with amikacin.

Case records of 1,098 patients treated with amikacin at 79 research centers in 10 countries in a program of worldwide clinical trials were reviewed. Of the 697 patients eligible for use in evaluation of efficacy of the drug, 81% were cured, as evidenced by clinical remission and eradication of the infecting pathogen. The usual dosage was 7.5 mg/kg administered intramuscularly at 12-hr intervals. This dosage was modified in patients with renal impairment. Amikacin was effective in 90% of 322 patients with genitourinary infections, 85% of 97 patients with septicemia, 70% of 73 patients with infections of skin, soft tissue, or bone (excluding burns), and 69% of 68 patients with infections of the lower respiratory tract. Amikacin was effective in treatment of 88% of 85 infections due to gentamicin-resistant pathogens. The drug was generally well tolerated, and no side effects were reported in 80.6% of the 1,098 patients evaluated. Amikacin shares with other aminoglycosides the risk of ototoxicity and nephtotoxicity; previous exposure to gentamicin was a major factor in the development of such adverse effects. Other adverse reactions were relatively infrequent and in most cases were characterized as mild and transient.

Adolescent↗
PubMed1975

The two-professional marriage: a new conflict syndrome.

The two-professional marriage that begins during the period of preprofessional or professional training is apt to break down during the immediate postraining period. Reasons for this occurrence are discussed in the light of marital dynamics and adult developmental issues, with special emphasis on female professional role development.

Divorce↗