Biomedical subjects
Publications and source records attributed to E Bertram.
The reliability of CKMB for diagnosis of cardiac damage in cases of thoracic contusion is tested in dogs. Results show that increased level of CKMB identificates the risk group of heart contusioned patients early and clearly, so that an continuous supervision of these patients can be established.
In Wistar rats, bile was drained by biliocutaneous fistulas 7 days after ligation of the common bile duct. Morphometric analysis using a computer program registered about 60 parameters of a hepatocyte. Most cell organelles are again normal 7 days after intervention. The ultrastructural changes are not fully compatible with histologic and biochemical findings.
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The reliability of CKMB in cases in which damage of sceletal muscles and myocardium occurred in close sequence is tested in dogs. Results show that in simultaneous damage of heart and muscles, CKMB exceeds the requested ratio of 5 to 8% of total CK, thus proving the myocardial infarction. In cases in which myocardial infarction succeeds a damage of sceletal muscle--e.g. a polytrauma --within distance of hours only, the absolutely high level of CKMB proves the infarction, even below the critical ratio of the total CK.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
In rat experiments a new silver chelate salt preparation is tested on scald wounds after standardized infection by Pseudomonas aeruginosa. 30% of the animals survive scalding and infection after treatment with the new cream. This percentage does not reach the gentamycin treated reference group (60%). After combining gentamycin and silver chelate salt in local therapy 75% of the animals survive. Combination of silver chelate salt and gentamycin seems to be a very successful local therapy of scald wounds.