[Body weight abnormalities in children with rheumatoid arthritis].
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Adolescent↗
Biomedical subjects
E Bogdan
Publications and source records attributed to E Bogdan.
Comparative value of arm and leg exercise testing.
Arm exercise test (AET) is described as an alternative to the classical leg exercise test (LET). The value of these two types of exercise was studied in a group of 32 patients aged 34 to 65 years. The patients performed LET for several reasons and, after 24 hrs, AET under the same conditions. The effort level reached under LET was always greater than that achieved under AET and the calculated functional aerobic impairment (FAI) was 50% greater during AET thus supporting the idea that AET cannot be used instead of LET in determining the functional capacity (NYHA) of cardiac patients. However, AET remains useful for the determination of the occupational working capacity in certain occupational categories. The double product (DP) (or index tension time (ITT) calculated after AET represented 85% of the calculated value after LET. The results proved that MVO2 is similar for both LET and AET, but in the latter at lower levels of exercise (VO2). The LET-DP was greater than the AET-DP in 66.5% of our cases, thus suggesting that AET should be reserved for situations in which LET cannot be performed. This is also supported by the presence of ST depression during AET in only 66% of the 18 subjects with ST depression during LET and in five of the six patients without ST depression, DP-AET was lower than DP-LET.
Adult↗
Does ischemic preconditioning occur during rehabilitation of ischemic patients?
Ischemic preconditioning is generally a short duration phenomenon, but during acute myocardial infarction a better inhospital outcome of patients with previous angina suggests that the effect of ischemic preconditioning could be longer than it was considered until now. It was also demonstrated that during successive exercise stress testings (ET) ST depression became lesser as a consequence of ischemic preconditioning. We investigated the possible occurrence of ischemic preconditioning during rehabilitation of ischemic patients. There were studied 43p with old myocardial infarction or stable effort angina, 29 men and 14 women, aged 33-68 years, divided in two groups: group I (19p) was included in a cardiac rehabilitation programme (15-20 sessions) and group II (24p) was not. All the patients were submitted to two ET at a month interval, for group I before and after cardiac rehabilitation programme. The peak-effort level was significantly greater for group I (80.26 +/- 7.2w vs 93.42 +/- 8.3w p < 0.05) but not for group II (65.5 +/- 5.8w vs 72.91 +/- 6.5w p > 0.05) during the two ET. The double product (21.573 +/- 3122 vs 24.168 +/- 3423 for group I and 23.551 +/- 3100 vs 21.000 +/- 2752 for group II) was not significantly different (p > 0.05) during the two ET. The same unsignificant modification was noted for maximal ST depression for group II (1.458 +/- 0.32 vs 1.166 +/- 0.21 mm p > 0.05) but not for group I patients in which maximal ST depression during the second ET was significantly less than during the first ET (1.52 +/- 0.23 vs 0.736 +/- 0.12 mm p < 0.05). Because cardiac rehabilitation does not influence the ischemic threshold and because the lesser maximal ST depression during the second ET was noted at the same, or even greater, double product (MVO2), we consider that it can be attributed to ischemic preconditioning.
Adult↗
Dipyridamole-exercise association in the diagnosis of ischemic heart disease.
Dipyridamole-exercise ECG test (DET) was found to present a greater sensitivity than exercise or dipyridamole ECG test alone in detecting ischemic heart disease (IHD). A group of 39 patients with probable IHD and negative exercise test was investigated by i.v. dipyridamole administration. Eight subjects presented significant ECG changes. The remaining 31 subjects were submitted to a new exercise test which became positive in 7 subjects (23%). The percentage increases to 38% by taking into account the positive dipyridamole test. The authors concluded that DET substantially improve the diagnosis of myocardial ischemia in subjects with probable IHD and negative exercise test.
Coronary Disease↗
Microalbuminuria, as predictor of late diabetic complications. A prospective study.
To assess the predictive value of microalbuminuria (M) for diabetic macro- and microangiopathy, neuropathy and some related risk factors studies were carried out in 105 diabetic subjects. All examinations were repeated after one year. Microalbuminuria was found to parallel all late diabetic complications, at the beginning of investigations and also after a one-year evolution. It also positively correlated with some risk factors for angiopathy, such as plasma lipid parameters, blood pressure, body mass index and duration of disease.
Adolescent↗
[The Barraquer-Simons syndrome (presentation of 2 cases)].
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Aged↗
The effect of low-dose amiodarone in prevention of paroxysmal atrial fibrillation.
The efficacy of amiodarone for atrial fibrillation (AF) prophylaxis is well established, but the large doses used until recently may be harmful during long-term therapy, especially because of the pulmonary fibrosis it generates. Recently, similar good results have been reported in using low-dose amiodarone. We studied the prophylactic effect of long-term therapy of low-dose amiodarone (200 mg/day) in 26 patients with AF of various etiologies. During a period of six months to four years, 46% of patients were free of any arrhythmic attack. The paroxysmal attacks of AF continued in 35% of patients, but with a lower frequency. In 19% of patients AF became chronic during amiodarone therapy. The best results were registered in patients over sixty, with stable sinus rhythm in 75% of cases, probably in relation to the ischemic etiology of AF and the anti-ischemic associated effect of amiodarone. The stability of sinus rhythm was greater (50% vs 38%, p < 0.05) when the treatment with amiodarone was started within the first six months from the first AF attack. Our results supported the use of low-dose amiodarone as a first-line drug for the long-term prophylaxis of AF, mainly in older patients.
Adult↗