A simple micro-method for time-kill studies amenable to routine laboratory use.
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Biomedical subjects
Publications and source records attributed to E Bouchet.
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BACKGROUND: Traditional neurological examination of newborns at risk for cerebral palsy (CP) is based on periodic assessment of normal milestones so that the diagnosis of CP can be very late. A complementary neuromotor evaluation based on two motor series has been proposed in order to make possible an early affirmation of integrity of motor paths. POPULATION AND METHODS: Eight hundred and seventy three infants including 371 preterms had been admitted to a neonatal intensive care unit from 1990 to 1992. Then, they were examined as outpatients by a multidisciplinary team. They were especially tested for lateral support on right and left superior limbs, alternately, and for lateral abduction reaction of each hip. RESULTS: Absence of manifestations of CP was noted in 87% of infants with a corrected age of 4 months; a correct prediction of future normal walking was made for all babies. Both tests could not be correctly performed by those babies who lately developed manifestations of CP. CONCLUSIONS: These two simple tests appear to be accurate to early predict normality.
In many cases the traditional neurological examination of high risk newborns for neurological problems secondary to perinatal difficulties does not identify easily the absence or the presence of cerebral palsy before walking. To help the neuromoteur follow up in these children, the authors suggest a complementary neuromotor examination that is successful only in normal infants. This examination is done in front of a mirror in the presence of the parents in order to increase the attention of the child, whose participation is necessary for a successful examination. Two motor responses are evaluated: the lateral support on, alternately, right and left superior limbs, and the lateral abduction reaction of the hip of each limb. When normal these two motor responses allow an early affirmation of integrity of motor paths if the examination is performed under carefully controlled conditions.
The use of urinary dipsticks to screen out sterile urine specimens was investigated in catheterized ICU patients. During a three-month period, each urine sample quantitatively cultured was concurrently tested at the bedside with a dipstick. A total of 102 urine samples taken from 43 patients were analysed. Thirty-eight of them showed bacterial or yeast growths (incidence rate, 37%). The negative predictive value of the leukocyte esterase pad and/or the nitrate test pad to screen out sterile urine samples was 81%, indicating that dipsticks cannot routinely be proposed to select catheterized ICU patients for quantitative culture of urine.