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Biomedical subjects

E Brach del Prever

Publications and source records attributed to E Brach del Prever.

8 recordsLinked to original sources

Unacceptable biodegradation of polyethylene in vivo.

The chemical characterization of 19 retrieved ultra-high-molecular-weight polyethylene tibial plateaux, six new ones and one raw bar was performed by means of infrared spectroscopy. The surface and bulk oxidation and biodegradation indexes were calculated. The raw bar has a measurable oxidation, which increases on the bulk and on the surfaces of the new plateaux. In the retrieved plateaux, the average oxidation index increases further both on the bulk and on the surfaces; the worse values were present on the worn area. Similar results were found for the biodegradation index. The data show that the biotic in vivo degradation is promoted by the oxidation present on the new plateaux and that it occurs through a different mechanism, abiotic thermal-, photo-, gamma-radiation oxidation, evaluated by the oxidation index.

Aged↗

Biocompatibility and osteogenetic characteristics of new biocompatible glasses.

A fibre-shaped glass with qualities of biocompatibility and biodegradation could be promising for reconstructive bone surgery in orthopaedics and neurosurgery. New highly biocompatible glasses, originally made by the Italian Group of Study on Biocompatible Glass, are obtained both in cylinder and fibre shapes due to their original chemical composition (Glassfiber). This is the only glass which is also available as a continuous filament. Hydrolytic in vitro and in vivo tests demonstrate that these glasses present both good biocompatibility and adjustable biodegradation in relation to their chemical composition. The advantages of bioactive glass also being available as a continuous filament are suggested.

Animals↗

Osteochondritis dissecans of the femoral condyles. A histological study with pre-operative fluorescent bone labelling and microradiography.

A review of the literature in osteochondritis dissecans of the femoral condyles reveals that the aetiopathology is still unclear and that relatively few histopathological studies have been carried out. The authors describe a method of study based on microradiography and on preoperative fluorescent labelling of the osteogenetic area followed by examination of the bone remodelling under ultraviolet light microscopy. The results in 12 adult cases are reported in relation to a topographical scheme which divides the lesions into four separate zones.

Adult↗

Mittelmeier's prosthesis: histological and microradiographic study two years after operation.

The writers present the results of the histological and microradiographic study of a femur and acetabulum two years after the implantation of Mittelmeier's prosthesis, the patient having died from an accident. The periprosthetic diaphyseal cortical bone had been fully resorbed, spongy bone had developed in the central portion and subperiosteal elongated lacunae had formed in the antero-medial part. The sclerosis at the calcar and at the apex of the shaft was made up of osteone systems, part of which consisted of newly laid down bone. The periprosthetic osteofibrous layer was separated from the cortical bone by wide inter-trabecular spaces except in the lateral sector where the shaft was supported by cortical bone that had been relatively conserved.

Acetabulum↗

Mittelmeier hip prosthesis autopsy study 2 years after implantation.

A Mittelmeier hip prosthesis was removed at autopsy 2 years after implantation in a patient who was fatally injured. Macroscopic, histological, radiographic, and metrological studies revealed interesting new aspects on the remodelling of bone and the behaviour of the components of the prosthesis.

Acetabulum↗

CT evaluation pre- and post-percutaneous ablation by radiofrequency of osteoid osteoma. Preliminary experience.

PURPOSE: Evaluation of bone remanagement after treatment by thermoablation of osteoid osteoma (OO) by CT scan. MATERIAL AND METHOD: Nine cases of OO (8 in the limbs, 1 in the pelvis) following biopsy were treated by CT-guided thermoablation. Clinical results, complications, density of tissues treated by CT scan (pre-postop, 6, 12 months) are evaluated. RESULTS: Absence of complications, regression of pain over 2 weeks, resumption of sports activity in 1 month. Bone density after treatment increases but even after 1 year it is much lower than normal levels. CONCLUSIONS: Bone remodeling after thermoablation of OO requires much time, the process is still visible 12 months later by CT scan. CT scan is an adequate method, not only for diagnosis and treatment, but also for follow-up, capable of evaluating in time the changes in density of the site of the lesion, which is useful for a comparison in case of postoperative pain of doubtful origin.

Adolescent↗