[Structure and C 13 -chemical shift of natural substances: pulse-Fourier-transform C 13 -NMR spectroscopy of riboflavine].
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Biomedical subjects
Publications and source records attributed to E Breitmaier.
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1,4-Epidioxy-bisabola-2,12-diene (3) and aromatic hydroperoxides (4, 5) were prepared by photoxidation of gamma-curcumene (1). Reduction and esterification of 6 and 7 afforded compounds 9 to 10. All compounds were tested in vitro for antimalarial activity. The activity could not be increased significantly, compared with 3. The most active compounds, 3 and 9, did not show in vivo antimalarial activity in mice.
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