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Biomedical subjects

E Bruijnes

Publications and source records attributed to E Bruijnes.

10 recordsLinked to original sources
PubMed1998

[The relationship between the serum level of prostate specific antigen and bone and CT scans in the staging of the primary carcinoma of the prostate].

OBJECTIVE: To determine the relationship between the serum level of prostate-specific antigen (PSA) and the presence of abnormalities in a skeletal or CT scan in patients with primary carcinoma of the prostate. DESIGN: Retrospective. SETTING: Academic Medical Centre, Amsterdam. PATIENTS AND METHODS: The serum PSA levels were compared with the findings in the skeletal and CT scans of 440 patients with carcinoma of the prostate without clinical signs of metastases, seen in the period from January 1990 to December 1994 in the outpatient clinics for Urology of the Academic Medical Centre (AMC) in Amsterdam, Hospital Gooi-Noord in Blaricum and Hospital De Heel in Zaandam. CT scan data were analysed only from the AMC and Hospital Gooi-Noord. RESULTS: There were 76 patients with a positive bone scan (17.3%) and 31 (out of 337; 9.2%) with a positive CT scan. Higher PSA serum levels went together with increasing risk of abnormalities in bone or CT scan. Of 85 patients with PSA values < 10 micrograms/l, none had a positive bone scan and one (out of 73; 1%) a positive CT scan; of the 180 patients with PSA levels < 20 micrograms/l, 4 (2.2%) had a positive bone scan and 2 (out of 154; 1.3%) a positive CT scan. The T stage, the histological grading and the serum alkaline phosphatase activity appeared not to have any supplementary value. CONCLUSION: In view of the low frequency of abnormalities in a bone or CT scan in patients with low PSA levels, it appears justified no longer to recommend bone or CT scanning for staging of patients for a clinically non-metastasized carcinoma of the prostate and serum PSA levels < 20 micrograms/l.

Aged↗
PubMed1986

Simultaneous measurement of pressure profile and pull-through force in the urethra of 25 female patients.

Simultaneous registration of urethral pressure profile and pull-through force was performed to study the dynamics of sphincteric function in 25 female patients. Three separate types of catheters of six different sizes were used. A 6-French smooth catheter was used to measure maximal urethral closure pressure, functional profile length and length to maximal urethral pressure. The results were divided into three groups (A, B and C) with significantly different closure pressure values, only correlated to the age of the patient. In all three groups (A, B and C), the mean maximal urethral closure pressure increased in linear correlation to the catheter diameter and did not bear any relation to the shape of the catheter tip, either of the bulb or the ball type. A significant exponential correlation was demonstrated between pull-through force and catheter diameter. Also the correlation between force and length of the pull-through force curve was exponential, while only the mean values of closure pressure and force correlated exponentially. No further correlations were found, even after force values were ranked to form three other groups (I, II and III). In contrast to the groups A, B and C, no distinct differences in clinical diagnosis was noticed between groups I, II and III. The pressure and force curves can be explained on a physical basis, despite the variety in pathology. On the basis of this evidence it appears that a more accurate measurement of sphincter function in the female can be obtained by measuring pressure and force simultaneously with different sizes of catheters, especially with a diameter of 15 French or more.

Adolescent↗
PubMed1985

The inverted urothelial papilloma.

3 additional cases of inverted urothelial papilloma are presented. A pathological, clinical and epidemiological review of this rare urothelial lesion is given.

Aged↗
PubMed1985

Congenital polyp of the prostatic urethra in childhood. Report of 3 cases and review of literature.

Congenital polyps of the prostatic urethra are supposed to be rare benign hamartomatous protrusions of the urethral wall in infants. The core contains predominantly connective tissue with cellular constituents of the lamina propria, but also smooth muscle cells, islets of glandular cells and even nerve tissue have been described. The core is lined by transitional epithelium, but in several cases squamous metaplasia has been reported. Because the polyp may act as a ball valve, mainly obstructive symptoms are presented. Suprapubic approach is generally recommended resecting a polyp; however, smaller lesions are accessible to transurethral resection. Three cases presenting different symptoms are reported. In 1 patient the polyp contained keratinized squamous epithelium.

Adolescent↗
PubMed1984

Fibrous pseudotumor of the tunica vaginalis testis.

The incidence of fibrous pseudotumor of the tunica vaginalis testis is rare. It is a benign, fibroproliferative process with hyalinization and sometimes with focal calcification. In most cases malignancy is suspected although by careful physical examination it may be possible to establish the diagnosis pre-operatively. The best form of therapy is frozen section biopsy of the pseudotumor followed by excision; including if necessary the tunica vaginalis. If the pseudotumor is locally extensive an epididymectomy is sometimes necessary. A study of the literature reveals that because of the rarity of this lesion orchidectomy appears to have been performed in most cases. A case report of a patient with fibrous pseudotumor of the tunica vaginalis testis is presented.

Adult↗
PubMed1984

Fibroepithelial ureteral polyps.

Two cases of fibroepithelial polyps of the ureter are reported. In one case the polyp was protruding through the meatus of the urethra whereas in the other case no clinical manifestations were observed. Both benign tumors were treated by local surgery. Etiology, clinical features, diagnosis and therapy are discussed.

Adult↗
PubMed1979

Experience with a newly developed automatic uroflowmeter.

An automatic cabin uroflowmeter was developed in order to guarantee the privacy of the patient, to simplify the measurement, and in particular, for screening. The meter is based on the method of von Garrelts, and the registration is performed with a music cassette. After an extensive calibration, 76 measurements from 22 persons without urologic complaints and 42 measurements from patients were analyzed. The obtained values of the control group, as well as those of the patient group were comparable to the data mentioned in literature. A normogram is presented correlating maximum flow rate and voided volume.

Adult↗
PubMed1978

The ureteral pressure profile: an experimental study in canine ureters.

In 10 anesthesized mongrel dogs ureteral pressure profiles were obtained with two types of high density polyethylene catheters. During the profilometry X-ray image intensification was performed. The data obtained from both ureters and also from both types of catheters did not show any statistically significant difference (p less than 0.05). Near the uretero-vesical junction a statistically significant biphasically shaped graph with mean pressures of 89.2 +/- 5.25 and 81.7 +/- 8.43 (SEM) mm Hg for the proximal and distal top, respectively, was seen (p less than 0.05). This phenomenon corresponds with the morphology, as mentioned in literature and as investigated in this experiment by X-ray photographs at post-mortem specimens.

Animals↗
PubMed1978

The pressure profile of the common bile duct an experimental study in 15 mongrel dogs.

In clinical urology the urethral pressure profilometry, developed by Brown and Wickham in 1969, is a well known diagnostical method. To our knowledge this type of investigation was not made in the common bile duct. In order to evaluate this method as an eventual clinical preoperative endoscopic method, especially in disorders of the choledocho-duodenal junction, choledochal pressure profile studies were made in 15 anesthesized mongrel dogs via a duodenotomy. The method was made according to the internationally advised standards of the urethral pressure profilometry. The mean contact basal pressure level in the choledochal duct amounted to 10,9 +/- 2,17 (sem) mm Hg. A statistically significant biphasis pressure elevation was seen in the region of the choledocho-duodenal junction (p less than or equal to 0,05). The mean pressures of the proximal and distal pressure elevation amounted to 59,8 +/- 8,51 (sem) mm Hg and to 54,3 +/- 7,13 (sem) mm Hg. The proximal top was located at 3,68 +/- 0,28 (sem) cm and the distal top at 0,96 +/- 0,07 (sem) cm distance from the orifice of the papilla. The total length of the elevated pressure zone amounted to 5,50 +/- 0,29 (sem) cm and the length of the elevated pressure zone of the distal top was 1,58 +/- 0,10 (sem) cm. These data correlate with the morphological structure of the choledocho-duodenal junction as mentioned in literature and illustrated with X-ray investigation and casts of the distal choledochal lumen. Our data show that with choledochal pressure profilometry pressure and length of the sphincter of Oddi can easily and safely be determined. In combination with endoscopy the technique can be of value in preoperative and postoperative evaluation of the function of the choledocho-duodenal junction.

Animals↗