Biomedical subjects

E C Barbosa

Publications and source records attributed to E C Barbosa.

5 recordsLinked to original sources

PubMed1992

[Hypocalcemia causing heart failure].

A 39-year-old female patient with refractory heart failure has been studied. On February, 1982 she was submitted to right lobar thyroidectomy for remotion of the left thyroid lobe. Following the surgery, she had signs of hypocalcemia and the diagnosis of secondary hypoparathyroidism and heart failure had been made. Seven months after she had acute pulmonary edema, cardiomegaly III (cardiothoracic index = 0.58) with predominant left atrial and left ventricular hypertrophy, which were confirmed by echocardiogram (ECO). The ECO also demonstrated low contractility of the left ventricle. The QT interval was increased on the electrocardiogram (QTc = 0.50 s), the calcium was 5.0 mg/dl with calciuria of 28 mg/day; phosphatemia was 4.8 mg/dl and phosphaturia of 214 mg/day. The level of thyroid hormones (T3 and T4) were in the normal ranges despite the TSH was increased in the beginning of the disease. She was first treated with digitalis, diuretic and vasodilator drugs, thyroid hormone and oral calcium. She had progressive hemodynamic improvement when higher doses of calcium were given with D3 vitamin. The most significant result of this treatment was reduction of the heart size that come back to normal. At the present time patient is treated with thyroid hormone, calcium and D3 vitamin only.

Acute Disease↗

PubMed1991

[Significance of prolonged PR interval in patients with His bundle branch block, bifascicular type].

PURPOSE: Evaluation of the prolonged PR interval and its predictive value for trifascicular block in individuals with bifascicular His bundle branch block. PATIENTS AND METHODS: 55 patients, 36 male and 19 female aged 57 + 15.8 years with bifascicular bundle branch block type have been studied. 11 cases had complete left bundle branch block and 44 cases had complete right bundle branch block with left anterior and superior division block. His bundle electrogram and atrial stimulation were performed in all patients. The atrial stimulation rate originating the Wenckebach phenomenon (SP) of the A-V conduction, and the A-H and H-V intervals were compared with the PR interval of the surface electrocardiogram. Patients were divided into three groups according to the PR interval: group I, Pr less than 200 ms, group II, PR between 190-280 ms and group III, PR greater than or equal to 280 ms. RESULTS: There was not linear correlation between the PR interval and WP in the three groups. There was a weak linear ascending correlation between the PR and A-H intervals in groups I and II (r + 0.59 and + + 0.43, respectively) and there was a descending correlation in the group III (r. - 0.64, P less than 0.05). In relation to the H-V interval there was not linear correlation with the PR interval in groups I and II, but there was a good ascending linear correlation in the group III (r 0.84, P less than 0.01). The incidence of prolonged A-H and H-V intervals increased as the PR interval was larger. CONCLUSION: The prolonged PR interval with bifascicular bundle branch block means, in the majority of cases, diffuse damage of the conduction system involving the A-V node and the infranodal region; starting from 280 ms, the delayed PR interval suggests involvement predominantly below the A-V node: to a higher PR interval corresponds a higher H-V interval and also, to a relatively shortest A-H interval.

Bundle of His↗

PubMed1991

[Evaluation of syncope in patients with chronic Chagas heart disease].

PURPOSE: To evaluate causes of syncope in patients with Chagas' disease and intraventricular conduction disturbances. METHODS: Nine patients have been studied, being seven males. Average of 49 years. The studied consisted of His Bundle electrogram, determination of Wenckebach period (WP), sinus node recovery time (SNRT), atrial stability and programmed ventricular stimulation (PVS). RESULTS: Monomorphic ventricular tachycardia (VT) was induced in five patients (55.5%), WP depression was observed in three cases, H-V interval prolongation occurred in three cases and the SNRT was normal in hall patients. In one case the electrophysiological study was completely normal. Among five patients with induced VT, with a mean follow-up period of seven months, one died suddenly, three became asymptomatic with antiarrhythmic drugs and one went on a non pharmacological therapy. In the other four patients with a mean follow-up period of 21 months, three are asymptomatic and one presents occasional dizziness (patient with a normal study). Among the patients with VT four presented recurrent syncope while in the group of patients without VT (four patients) all had only one syncopal episode. CONCLUSION: Patients with intraventricular disturbances, Chagas' disease and syncope, VT may be responsible for the symptoms in approximately 44% of cases. The PVS must be considered as a routine in the investigation of these patients.

Adult↗

PubMed1991

[Evaluation of the PR intervals in normal and prolonged maximum limit with short QRS].

PURPOSE: Evaluation of the A-V node function by determining the Wenckebach period (WP) and atropine response in cases of normal PR interval, PR interval at maximum normal range and prolonged PR interval, all with short QRS. PATIENTS AND METHODS: 129 patients, 79 male and 50 female, aged 17 to 84 years (mean 59), asymptomatic or with complaints of palpitations, dizziness, presyncope or syncope has been studied. ECG showed supra-ventricular tachycardia, first degree A-V block or intermittent Mobitz I type A-V block and sick sinus syndrome. Preexcitation (WPW) syndrome and longitudinal A-V dissociation were excluded. Electrical transoesophageal atrial stimulation was performed in all patients for evaluating the PR interval and WP. Atropine test was performed in a group of 16 patients. Based on the values of the WP, patients were divided into three groups: group I, WP greater than or equal to 125 ppm (N = 88); group II, WP ranging 125-110 ppm (N = 16) and group III, WP less than or equal to 110 ppm (N = 25). RESULTS: There was a good decreasing lineal correlation between the PR interval and the WP only in the group III (r = 0.76, p less than 0.01). PR interval greater than 240 ms had greatest and significant incidence in the group III in relation to the other groups in which the number of WP post-atropine normalization was observed. CONCLUSION: There is a strong linear decreasing correlation between the PR interval of the ECG and the WP in individuals with WP less than or equal to 110 ppm. PR interval greatest than 0.24 ms corresponds better to WP below 110 ppm (mean 90 ppm) and the majority of these patients do not normalize the WP with the atropine. We suggest the term "first degree A-V block" for those cases with PR interval greater than 240 ms and "A-V depression" for the cases with PR interval shorter than 240 ms when recorded on the surface electrocardiogram and have been normalized with atropine.

Adolescent↗

PubMed1989

[Significance and prognosis of ventricular extrasystole induced by exertion in patients with arterial hypertension with a normal electrocardiogram].

We studied 13 patients with systemic arterial hypertension and normal electrocardiograms so as to evaluate the significance and prognosis of frequent and complex ventricular premature beats (VPB) induced by exercise testing. After a period of 9 to 33 months of follow-up (mean = 17.6 months), we repeated the exercise testing with the same protocol in all cases. In nine patients (69.2%), the arrhythmia disappeared during exercise, two increased the number of VPB and two others reduced the number of the arrhythmia. Complications, such as sustained ventricular tachycardia, were not seen in any case. The appearance of frequent and complex VPB with stress testing does not seem enhance the risk of sudden death or episodes of spontaneous ventricular tachycardia in patients with arterial hypertension but without electrocardiographic signs of cardiac hypertrophy.

Adult↗