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Biomedical subjects

E C Hanson

Publications and source records attributed to E C Hanson.

14 recordsLinked to original sources

Sodium hyaluronate--application in a community practice.

This office tracked the clinical results of 73 patients who received sodium hyaluronate for their knees, as well as two ankle patients and one elbow patient. A questionnaire designed to evaluate six areas of function-relief of pain, stiffness, walking tolerance, pain while negotiating stairs, swelling, night symptoms--was mailed to patients who had received the series of five sodium hyaluronate injections. Ninety-five percent of the questionnaires were completed and returned. We found that injectible sodium hyaluronate is a viable treatment option for properly selected patients, namely those with mild to moderate osteoarthritis of the knee. We found that it relieved pain and stiffness in most patients. The majority of patients were willing to repeat the treatment if necessary. Sodium hyaluronate allows the physician to relieve patient pain in early stages of the disease and to manage the patient comfortably until surgery is a viable option. With the appropriate precertification and billing protocol, reimbursement should not be an obstacle in using this product.

Adjuvants, Immunologic↗

Adhesive capsulitis of the wrist: arthrographic diagnosis.

Persistent pain and decreased range of motion are disabling complications of wrist trauma. Between 1978 and 1986, in ten patients with persistent pain following trauma, arthrography depicted changes characteristic of adhesive capsulitis. Adhesive capsulitis has been described in the shoulder, hip, and ankle, but little mention has been made of this entity in other joints. Confirmation of this diagnosis requires arthrography, since there are no characteristic findings on plain radiographs. Typical arthrographic findings include decreased capacity, small volar and styloid recesses, and adhesions preventing complete opacification of the joint. The arthrographic diagnosis allows proper institution of appropriate therapy.

Adult↗

Adhesive capsulitis of the wrist. Diagnosis and treatment.

Adhesive capsulitis occurs as a pathologic entity in the shoulder, hip, and ankle joints. Thickening and contracture of the wrist joint capsule were demonstrated on arthrograms performed on ten patients ranging in age from 20 to 82 years. The patients had pain and limited range of motion in the wrist. The findings included: (1) resistance to the injection of smaller than normal volumes of contrast material, (2) obliteration of recesses, and (3) extravasation of the contrast agent along the needle tract. Closed manipulation under general anesthesia of the wrist on four patients resulted in some improvement in range of motion. A distal ulna fracture in one older patient occurred as a complication of manipulation. Careful technique and judicious patient selection are of paramount importance.

Adult↗

The surgical treatment of atrial myxomas. Clinical experience and late results in 33 patients.

Thirty-three patients (28 female and five male) from 17 to 70 years of age (mean age 48 years) underwent excision of left atrial myxomas between 1957 and 1981 at The Cleveland Clinic Foundation. Twenty-four patients presented with congestive heart failure, three with tachyarrhythmias, two with syncope, and one each with angina, peripheral embolization, hemoptysis, and recurrent pleural effusions. Symptoms were present from 1 to 72 months before operation (mean 11.2 months). Thirty-one tumors originated from the atrial septum and two from the mitral valve anulus. Twenty-nine tumors were pedunculated, and four were sessile; they weighed from 20 to 112 gm (mean 57 gm). No right atrial or ventricular tumors were identified. The myxomas were successfully removed in all patients, either by shaving them from the atrial septum (n = 17) or by excising a portion of normal atrial septum with the tumor (n = 16). One death (3.0%) occurred 8 days after operation as a result of multiple tumor emboli to the coronary circulation. Follow-up is current and complete in all cases (range 1 to 25 years, mean 6.7 years). Twenty-eight patients are in New York Heart Association Class I, and the remaining four patients are in Class II. No recurrent myxomas have been identified clinically or by echocardiography in any patient. Altogether, 24 patients have been studied by two-dimensional echocardiography up to 20 years after operation (mean 4.0 years). In this series, excellent results were obtained by simple excision of the tumor, with or without a margin of normal atrial septum. Long-term clinical and echocardiographic follow-up is recommended since late recurrence, although rare, has been reported.

Adolescent↗

Hyperlipoproteinemia as a significant risk factor for pulmonary embolism in patients undergoing coronary artery bypass grafting.

A five-year (1975 through 1979) retrospective analysis of all cardiac surgical patients who sustained a postoperative pulmonary embolism was undertaken, and lipoprotein profiles of these patients were evaluated. Twenty-six patients (20 men and 6 women) were identified who had definite clinical, laboratory, and radiological evidence of pulmonary embolism in the postoperative period. Twenty had undergone coronary artery bypass grafting, and the remaining 6 had undergone other cardiac surgical procedures. Of the 20 patients who had coronary bypass, 19 (95%) were found to have hyperlipoproteinemia (14 patients with type II and 5 with type IV). There were 4 hospital deaths (15%), all related to pulmonary embolism. The 4 patients had undergone coronary bypass procedures, and all had type II hyperlipoproteinemia. Since patients with hyperlipoproteinemia made up less than 10% of the coronary bypass population, the incidence of pulmonary embolism in this group is highly significant (p less than 0.001). Experimental evidence has shown that patients with hyperlipoproteinemia, especially type II, have increased platelet adhesiveness and aggregation, and coagulation abnormalities consistent with a hypercoagulable state. This retrospective study clinically confirms that finding and suggests that early postoperative anticoagulation therapy may be indicated in patients with hyperlipoproteinemia, particularly type II, to reduce thromboembolic complications.

Coronary Artery Bypass↗

Retention of endodontic dowels: effects of cement, dowel length, diameter, and design.

The retentive capacity of three preformed endodontic dowel designs was compared at two lengths and two diameters, with three different cements. The greatest single factor influencing retention of these devices was the design used. Of the types tested in this study, the most retentive were threaded, parallel-sided dowels screwed into tapped channels. Serrated, parallel-sided dowels cemented in matched cylindrical channels provided intermediate retention, and smooth-sided tapered posts were the least retentive. Another major factor in retention was the length of imbedment into dentin. An increase in dowel imbedment depth usually corresponded to increased retention. The effect of cement type was significant only with tapered dowels. Zinc phosphate cement was most retentive, carboxylate cement exhibited intermediate retention, and the epoxy cement was least retentive. For the other post designs, cement type had no significant effect on retentive capacity. Finally, variations in dowel diameter had no significant effect on retentive ability.

Crowns↗

Neurogenic coronary vasoconstrictor effects of digitalis during acute global ischemia in dogs.

The rapid i.v. administration of digitalis has recently been shown to cause a substantial increase in coronary vascular resistance in the normal heart. This neurogenically mediated decrease in coronary blood flow would be potentially detrimental if it occurred during ischemia. The present study evaluates the effects of i.v. acetylstrophanthidin and digoxin on coronary vascular resistance during acute global ischemia in 29 dogs anesthetized with chloralose and urethane. Under these conditions, 0.5 mg of i.v. acetylstrophanthidin in 15 dogs resulted in erratic increases in coronary vascular resistance. The peak rise was 12+/-5% above control (P less than 0.01). In 7 of the 15 dogs, the initial erratic rise in coronary vascular resistance culminated in a steep rise associated with acute elevation in left ventricular end-diastolic pressure, which in four dogs terminated in ventricular fibrillation. During the nonischemic control periods, the peak rise in coronary vascular resistance with acetylstrophanthidin was 16+/-1% above control (P less than 0.01). In five dogs, prior alpha adrenergic receptor blockade with phenoxybenzamine prevented the rise in coronary vascular resistance with acetylstrophanthidin during ischemia. Similar erratic increases in coronary vascular resistance were observed with i.v. digoxin (1 mg) during ischemia in three dogs. In two of these dogs, there was a progressive rise in coronary vascular resistance associated with elevation of left ventricular end-diastolic pressure and ventricular fibrillation. The increase in coronary vascular resistance with digoxin during ischemia was abolished with phenoxybenzamine in two additional dogs. Thus, i.v. digitalis in the ischemic heart results in potentially detrimental increases in coronary vascular resistance mediated through alpha adrenergic receptor stimulation.

Animals↗

Effects of cement type and thickness on retention of serrated pins.

The retentive capacity of cemented pins was determined. Zinc phosphate, polycarboxylate, and cyanoacrylate were used to cement threaded pins (0.024 inch) into precise channels of 0.025, 0.026, and 0.027 inch. Highest retentive values were realized when zinc phosphate and polycarboxylate cements were used with the smallest pin-channel mismatch. Ethyl cyanoacrylate was least retentive and demonstrated no mismatch dependency.

Cyanoacrylates↗