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Biomedical subjects

E C Moorhouse

Publications and source records attributed to E C Moorhouse.

18 recordsLinked to original sources
PubMed1988

Efficacy of ofloxacin in the treatment of lower respiratory tract infections in general practice.

General practitioners assessed the efficacy and safety of ofloxacin in the treatment of lower respiratory tract infections in 100 patients. Treatment consisted of ofloxacin 200 mg twice daily for seven days. Evaluation of therapy was based on clinical and bacteriological parameters. Two patients were withdrawn from the study because of gastro-intestinal symptoms of nausea and vomiting. There were no significant drug-related alterations in haematological or biochemical parameters following treatment. Pathogens present in pre-treatment sputum specimens were eradicated from 63 of 66 patients. The overall assessment of response to treatment in the 98 evaluable patients was recorded as cured (45), much improved (47), slightly better (3), same (2) and slightly worse (1). It was concluded from these results that ofloxacin was both safe and effective in the treatment of lower respiratory tract infections.

Adult↗
PubMed1987

The international spread of methicillin-resistant Staphylococcus aureus.

A genetic analysis of representative methicillin-resistant Staphylococcus aureus (MRSA) being isolated in London and Dublin hospitals has demonstrated that the epidemic strains from two London hospitals are different from the Dublin strains, but indistinguishable from the epidemic strains of eastern Australia. The possibility that some strains of MRSA are more likely than others to spread within hospitals is discussed.

Australia↗
PubMed1985

The in-vitro activity of some antimicrobial agents against methicillin-resistant Staphylococcus aureus.

A total of 185 strains of methicillin resistant Staphylococcus aureus was investigated for sensitivity to five other antimicrobial agents. The vast majority of these strains were also resistant to gentamicin and fusidic acid. Rifampicin was the most active drug tested (MIC90, 0.007 mg/l), while two newer compounds teichomycin and ciprofloxacin showed equal and appreciable activity (MIC90, 0.5 mg/l).

Anti-Bacterial Agents↗
PubMed1983

Antibacterial prescribing patterns of doctors in the Irish Republic.

Antibacterial prescribing patterns of general practitioners and hospital doctors in a survey carried out this year (1982) were compared with those seen in previous surveys in 1977 and 1973. Since 1973, marked differences in preference for certain drugs in the treatment of urinary tract infection and diarrhoea were seen. Ampicillin, favourite antibiotic for treatment of respiratory infection in the previous surveys, remained first choice therapy in 1982 of both general practitioners and hospital doctors.

Anti-Infective Agents↗
PubMed1968

Infantile enteritis.

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Drug Resistance, Microbial↗