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Biomedical subjects

E C Vasilomanolakis

Publications and source records attributed to E C Vasilomanolakis.

8 recordsLinked to original sources
PubMed1985

Cardiac arrhythmias in a population admitted to an acute alcoholic detoxification center.

To characterize the relationship between acute alcohol ingestion and its withdrawal with cardiac arrhythmias, we studied 38 patients admitted to an acute community alcoholic detoxification center with 24-hour ambulatory ECGs and serum ethanol levels. We found a mild correlation between the serum ethanol level and the mean rate of ventricular ectopic beats/hour (rs = 0.34, p less than 0.05). Nonsustained ventricular tachycardia and atrial fibrillation were more common in patients found to have evidence of previous underlying organic heart disease. There was no change in the prevalence of cardiac arrhythmias in this population after 2 weeks of ethanol abstinence as judged by repeat 24-hour ambulatory ECG. We conclude that in patients admitted to an acute detoxification center, cardiac arrhythmias are found more commonly in those with underlying organic heart disease, and these arrhythmias do not appear to change after 2 weeks of abstinence from alcohol ingestion.

Adult↗
PubMed1985

Geriatric cardiology: when exercise stress testing is justified.

Short exercise duration is not necessarily ominous in an older patient unless other significant abnormalities, such as ST-segment depression or arrhythmias, are associated. Problems peculiar to the elderly during exercise testing--appearance of fatigue and lightheadedness due to muscle weakness and deconditioning, vasoregulatory insufficiency, and a tendency to unsteadiness of gait--may require physical or emotional support.

Aged↗
PubMed1984

Anaphylactic reaction due to zomepirac.

Zomepirac sodium is a nonsteroidal antiinflammatory drug with potent analgesic properties. Since its introduction in October 1980, this prostaglandin inhibitor has been fairly well tolerated, and little toxicity has been associated with its use. In fact, it was not until April 1981 that the first serious reaction of anaphylaxis was described. Since then six additional cases have been reported to the literature. The manufacturer voluntarily withdrew the agent in March 1983 from the market pending further investigation of these reactions. We describe the case of an additional anaphylactic reaction to zomepirac and review the literature.

Adult↗
PubMed1983

Cardiac rupture following intracoronary streptokinase.

Thrombolytic dissolution of coronary artery thrombus has added new dimensions to early myocardial infarction treatment. Reperfusion via streptokinase infusion has been shown to be beneficial; however, adverse effects are being noted. We present the case of a patient so treated who subsequently developed left ventricular free wall rupture.

Coronary Disease↗
PubMed1982

The effect of left ventricular aneurysmectomy on the electrocardiogram: a study of 77 patients and review of the literature.

UNLABELLED: Electrocardiograms (ECGs) were reviewed in patients undergoing left ventricular aneurysmectomy. Post-operatively, significant decreases were noted in ST segment elevation (p less than 0.001) and anterior (p less than 0.03) and inferior R wave heights (p less than 0.002). In addition, abnormal Q waves disappeared in 50% of patients. Comparison of ECG changes between survivors and patients dying of cardiac related events revealed that patients with a preoperative axis of greater than or equal to 60 degrees, postoperative leftward axis shifts and a marked decrease in ST segment elevation and/or R wave height had significantly higher mortality. CONCLUSION: 1) Left ventricular aneurysmectomy affects ventricular depolarization as evidenced by a significant loss of R wave height and changes in infarct pattern; 2) LVA affects ventricular repolarization as evidenced by a significant decrease in ST elevation; 3) the ventricular aneurysm appears to contain "viable muscle" that contributes to ventricular depolarization and remains partially depolarized during diastole; and 4) there are prognostic electrocardiographic parameters, which correlate with mortality during postoperative follow-up.

Adult↗
PubMed1980

Viomycin-induced electrolyte abnormalities.

Severe hypokalemia (2.6 mEq/l), hypomagnesemia (0.6 mg/dl), mild hypercalcemia (10.9 mg/dl), and secondary hyperaldosteronism developed in a patient receiving viomycin for pulmonary tuberculosis. Reversible renal wasting of both potassium (K+) and magnesium (Mg++) was documented. Viomycin administered to 40 rats resulted in severe damage to the proximal tubule and mild damage to the distal tubule. THe case report and experimental data suggest viomycin induces proximal tubule dysfunction that results in renal wasting of sodium, K+ and Mg++ and secondary hyperaldosteronism. Hypercalcemia, not previously associated with viomycin therapy, may be secondary to hypomagnesemia-induced hyperparathyroidism.

Adult↗