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Biomedical subjects

E Cabrera

Publications and source records attributed to E Cabrera.

50 records · Page 3Linked to original sources
PubMed1977

Contraceptive method continuation according to type of provider.

A study was undertaken at the main PROFAMILIA clinic in Bogota, Colombia to compare the effectiveness of nurses and physicians in the delivery of family planning services. Contraceptive method continuation was the major outcome variable in this analysis. Clients were randomly assigned to physicians or nurses on their first visit and for the duration of care. On all revisits, data were collected pertaining to method prescribed, side effects, pregnancy, and method changes. There was a field survey at eight months to locate clinic drop-outs and determine their contraceptive use status. There were no significant differences in method continuation between clients who received services from physicians and those who received services from nurses. At nine months, the overall continuation of the first method prescribed was 79.1 per cent in the physicians' group and 75.8 per cent in the nurses' group (t = 1.057, p greater than .20). When controlling for first method used, the IUD users in the physicians' group had a continuation rate of 86.1 per cent and in the nurses' group 84.0 per cent (t = 0.556, p greater than .50). Of the pill users who received services from physicians, 78.1 per cent were continuing at nine months and 74.3 per cent of the pill clients in the nurses' group were continuing at nine months (t = 0.573, p greater than .50). There were no differences in pregnancy rates, side effects rates, and method change rates between the two groups. It may be concluded that these nurses were as effective as physicians in the delivery of family planning services.

Adult↗
PubMed1976

An obligate osmophilic yeast from honey.

An obligate osmophilic yeast that requires high sugar concentrations (10 to 20% glucose) for growth was identified as Saccharomyces bisporus var. mellis. Optimum growth for this strain was at 60% glucose. Several non-assimilable compounds permitted growth at glucose concentrations below the minimum requirement and stimulated growth at glucose concentrations above the minimum. No correlation existed between growth stimulation and spheroplast stabilization capacities of the compounds examined.

Carbohydrate Metabolism↗
PubMedDate not supplied

Effect of irradiation dose, storage time and temperature on the ESR signal in irradiated oat, corn and wheat.

Results obtained for electron-irradiated oat, corn and wheat kernels are discussed. The applied irradiation doses were up to 160 kGy. For doses up to approx. 50 kGy the number of free radicals produced by the irradiation is linear with the absorbed dose; moreover, the decay at room temperature in the dark or in the presence of light is quite similar. These facts point to the possible use of these kernels as dosimeters. An analysis of the free radical decay as a function of time and temperature shows the contribution of at least three types of radicals, whose half-lifes, radiochemical yields and activation energies are given.

Avena↗
PubMedDate not supplied

Killing of gram-negative bacteria by ciprofloxacin within both healthy human neutrophils and neutrophils with inactivated O2-dependent bactericidal mechanisms.

The intraphagocytic killing of Escherichia coli, Serratia marcescens, Pseudomonas aeruginosa, and Salmonella typhi by ciprofloxacin (0.1, 1 and 5 microg/ml) within human neutrophils with intact and impaired (by phenylbutazone treatment) O2-dependent killing mechanisms was studied and compared with the extracellular killing in the same medium of the intraphagocytic killing, but omitting neutrophils. The MIC/MBC of ciprofloxacin in vitro (assays performed according to NCCLS specifications) were: 0.015/0.06 for E. coli, 0.12/32 for S. marcescens, 1/16 for P. aeruginosa, and 0.007/0.06 for S. typhi. Ciprofloxacin showed bactericidal activity both extracellular and within phenylbutazone-treated and untreated neutrophils. The minimum concentration of ciprofloxacin to kill 90% of phagocytosed bacteria within neutrophils with normal O2-dependent killing power after 30 min was: 0.1 microg/ml for E. coli, and S. typhi, 1 microg/ml for P. aeruginosa, and 5 microg/ml for S. marcescens. In contrast, exposure for 60 min was required to reach this percentage within phenylbutazone treated neutrophils. The minimum concentration to kill 90% of extracellular bacteria after 30 min was: 0.1 microg/ml for E. coli, P. aeruginosa and S. typhi, and 5 microg/ml, for S. marcescens. A positive interaction between ciprofloxacin and the O2-dependent mechanisms of phagocytes was found. The reactive oxygen metabolites produced in the respiratory burst did not affect the intraphagocytic activity of ciprofloxacin. Phenylbutazone treatment of phagocytes would be a good experimental model to study the intraphagocytic killing of drugs in situations such as AIDS and chronic granulomatous disease where inefficient oxidative mechanisms of neutrophils exist.

Anti-Infective Agents↗