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Biomedical subjects

E Cambau

Publications and source records attributed to E Cambau.

4 recordsLinked to original sources

[Bacterial population on the site of loss of cutaneous substance. Its role on the success of skin graft].

The bacterial population of 53 skin defects was studied together with its influence on the success of split skin grafts. All of the skin defects were found to be infected. Coagulase + Staphylococcus, group A beta-haemolytic Streptococcus and Pseudomonas aeruginosa were the micro-organisms most frequently isolated. The number of microorganisms does not influence the success of the graft. Streptococcus almost always causes failure of the graft in contrast with the other microorganisms which do not appear to have any specific influence. The anti-infectious strategy must therefore be selectively directed against this microorganism.

Graft Survival

[C-reactive protein: general review and role in the study of infections].

Known since 1930, C-reactive protein is, as serum amyloid P component its similar, part of acute phase response proteins. Its principals properties are short half-life (6-8 h), great (within 6 hours) and high (X500) rate after injury. It activates the classical complement pathway, leading further to bacterial opsonization. Different biological methods for measurement are described: both nephelometric laser method, most sensible, and agglutination-latex method, most simple and quickest, are chosen. Studies showed us that CRP value is interesting for diagnosis of bacterial infections: among them neonates infections, peri-partum infections, meningitis, pyelonephritis, pancreatitis or peritonitis. CRP value determination seems to be useful also to hold on with patients who keep infectious peril, as in post chirurgical following, neutropenic induced patients. It seemed to be no use for CRP measurement in grafts following. Its rate in inflammatory diseases or myocardial infarcts is just mentioned. The author precognize more determinations of CRP: in emergency laboratories for diagnosis of bacterial infections (agglutination latex method) and in "routine" to follow up the infectious peril.

Bacterial Infections

[In vitro bleeding time].

An in vitro model of primary haemostasis, in vitro bleeding time (BT) according to Kratzer and Born, was studied. There was a significant correlation with in vivo BT. The in vitro BT may be easily repeated in the same patient, facilitating the control of haemostasis. It may also permit studying the effect in vitro and/or ex vivo of drugs on primary haemostasis.

Bleeding Time