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Biomedical subjects

E Campailla

Publications and source records attributed to E Campailla.

At least 19 recordsLinked to original sources

Mimickry in osteogenic sarcoma. Clinical considerations and report of 2 cases.

The authors report two cases of osteogenic sarcoma which presented under the false diagnosis of aneurysmal bone cyst and benign fibrous histiocytoma respectively. This mimickry is discussed: a) It is certainly more common than would appear from the literature, particularly in the case of aneurysmal bone cyst; b) this mimickry applies particularly to the lytic type of osteosarcoma; c) the adjective telangiectatic which is often used to describe malignant bone aneurysms is equivocal; d) immature forms of osteogenic sarcoma all possess a common factor with regard to onset, course and outcome of the disease; e) microscopic anaplastic elements may not always be observed in these imitations; f) clinical examination may often achieve or at least get closer to a true diagnosis of the disease: it is necessary to be aware of the existence of mimetic forms of osteogenic sarcoma and carefully evaluate all the available information; g) surgery should be delayed where clinical doubt exists and the histological report is negative. Such a delay may allow the tumour to reveal its true nature so that the surgeon and oncologist can select the correct treatment.

Adolescent

[Surgical treatment of lesions of the cruciate and collateral ligaments of the knee].

The paper describes a number of patients operated for recent lesions of cruciate anterior ligament associated with lesions of internal collateral ligament. Patients were controlled after a time from operation of a 4 months- 4 years. For an exact functional valuation, a personal protocol was used, elaborated from the methods of the Orthopedic School of Lion. In the majority of cases, the trauma was secondry to sport practice, expecially sky. The technique used were the O'Donoghue one for cruciate ligament and the Vigliani one for collateral. Results were in all cases very good.

Humans

[Surgical treatment of pertrochanteric fractures with Ender's intramedullary nails].

Endomedullary nailing by Ender technique is a new method of metallic synthesis for perthrocanteric and subthrocanteric fractures. The difference with the other methods of ostheosinthesis is given by an elastic sinthesis of dynamic type, with endomedullary pins. The surgical technique is easy, not excessively stressing, very rapid. A surgical approach to distal femoral metaphysis is necessary; successively three or four particular metallic pins are put inside the medullary space, in proximal direction. This technique given excellent results in 50% of cases; good results in 25%; poor in 15%. The postoperatory mortality is particular limited amounts only to 10% (with an average of 78 years).

Aged

[A review technique: the interscalene brachial plexus block in orthopedic surgery (author's transl)].

The paper is dedicated to the description of a technique now new but also not very used, of regional anesthesia, indicated for surgery of upper limbs: the interscalene brachial plexus block. In Author's experience this type of anesthesia has many indications, related especially to orthopedic and traumatologic surgery, in patients with high anesthesiologic danger. This type of regional anesthesia by interscalene technique is, in Author's opinion, much better than the axillar technique, now moore frequently used.

Adolescent

Meta-echinococcal arthrosynovitis: a clinical, anatomical and pathological entity not previously recognised.

The authors describe a case of echinococcosis of the tibia which occurred twice in seven years, the first time with signs of active involvement of the knee joint. Certain special aspects of articular echinococcosis, not up to now reported in the literature, are dealt with. The conclusion reached is that in an articular site the parasite can give rise either to a veritable "echinococcal" arthritis or, as in the case presented, to a the synovial affection which cannot be defined as "echinococcal" because the synovium did not contain living larval forms of the parasite, but only microscopic chitinous inclusions, arising from the disintegration of sterile hydatids, which had escaped from the adjacent bony focus into the joint. The synovium reached to their presence with an intense inflammatory response of a predominantly histiocytic nature. The term "meta-echinococcal arthrosynovitis" is suggested as a more accurate designation of this syndrome.

Adolescent

Neurotic rachialgia.

After a discussion of the term "benign dorsalgia," and a description of the clinical picture of the syndrome, the term "neurotic rachialgia" is proposed as being more exact. In fact, pain is not always referred to the dorsal tract of the spine but to other areas as well. Furthermore, the syndrome is an expression of a neurotic condition. Diagnosis is based on exclusion: no clinical or radiologic signs are demonstrable. The utility of "relaxation therapy" is described by several technics.

Back Pain

Stimulation of 45Ca efflux from smooth muscle cells by metabolic inhibition and high K depolarization.

The characteristics of the extracellular and cellular calcium exchange in taenia coli have been studied by efflux experiments under different experimental conditions. The exchange of extracellularly bound calcium is accelerated by the presence of calcium in the external solution. If a Ca-free solution is used as washing solution, the slowly exchanging extracellular calcium also contributes appreciably to the later phase of the Ca efflux and obscures the changes of the cellular calcium exchange. There is no evidence for a Ca-Ca exchange diffusion. Most of the 45Ca bound at extracellular binding sites can be released by a 10 min exposure to 2 mM EGTA or to 10 mM La3+. This La concentration moreover largely inhibits the release of 45Ca from the cellular compartment by metabolic depletion. A release of cellular 45Ca can be induced by metabolic depletion or by K depolarization. Both procedures probably act at the same sequestering sites. However, while DNP + IAAa cts in the absence of external Ca, it is observed that K depolarization can only cause a Ca release if external Ca can enter the cells.

Adenosine Diphosphate

[Cerebral malformation and thanatophoric nanism].

Report of one case of atypical osteo-chondrodysplasia, which was classified as a thanatophoric dwarfism, with neuropathological examination of the brain. Microgyria and cytological changes were in the ectocinerea. Too heterotypies in the neuronal place were observed.

Abnormalities, Multiple

Dyschondrosteosis.

The authors present three cases of dyschondrosteosis occurring in a single family unit. The characteristics of the "major" and "minor" forms of this genetically derived chondrosteodysplasia are described. The other members of the family examined presented no signs of the disease, but they were very young. The possibility of successful surgical correction of the deformities caused by dyscondrosteosis is stressed.

Bone Diseases